Growth of Asymptomatic Intracranial Fusiform Aneurysms : Incidence and Risk Factors

Clinical Neuroradiology
Jusun MoonMoon Hee Han

Abstract

Growth of intracranial fusiform aneurysms (IFA) may become clinically problematic through a mass effect or rupture. We investigated the growth rate and factors contributing to growth in asymptomatic untreated IFA. As a retrospective review, we assessed patients diagnosed with asymptomatic IFA between August 2000 and September 2014, all untreated. No acute or symptomatic dissecting lesions were considered. Clinical and serial angiographic follow-up data were analyzed, defining growth as expansion > 2 mm in one or more dimensions. A binary logistic regression model and Kaplan-Meier method were applied for statistical analysis. The mean follow-up in the 82 eligible patients was 47.7 months (range 12-190 months). Among them, 7 aneurysms (8.5%, 2.1% per aneurysm year) demonstrated growth (in any dimension). In univariate analysis, height and multiplicity of aneurysms emerged as significant factors in terms of growth. Height remained an independent risk factor in the binary logistic regression model, with receiver operating curves indicating a threshold of 6.9 mm initial height in determining IFA growth (area under the curve 0.804). Of the patients six (except one who underwent endovascular treatment) were observed during continued f...Continue Reading

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Citations

Jun 4, 2020·Asian Cardiovascular & Thoracic Annals·Saad Moughal, Mohamad Bashir
Feb 27, 2021·Journal of Neurointerventional Surgery·Ryan Phillip SabotinEdgar A Samaniego
May 22, 2021·World Neurosurgery·Yoshinobu HorioTooru Inoue

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