PMID: 6968334Oct 1, 1980Paper

Growth of factor-dependent hemopoietic precursor cell lines

The Journal of Experimental Medicine
T M DexterD Metcalf

Abstract

Cell lines have been produced from long-term cultures of mouse bone marrow that require a factor, present in WEHI-3 conditioned medium (CM) or in spleen CM, for their sustained growth. The cell lines were obtained from nonvirus-treated cultures, are nonleukemic, maintain a normal karyotype, and form colonies showing granulocyte maturation when plated in soft agar. Granulocyte/macrophage (GM) colony-stimulating factor is not the inductive moiety involved in the maintenance of proliferation of these cells. It is suggested that the cell lines represent a self-renewing population of cells ancestral to GM colony-forming cells, which may be responding to a hitherto unrecognized regulator.

References

Jun 1, 1977·Journal of Cellular Physiology·T M DexterL G Lajtha
Feb 1, 1979·Journal of Cellular Physiology·D MetcalfT E Mandel
Nov 1, 1976·British Journal of Haematology·B I LordL G Lajtha
Dec 1, 1970·Virology·W P RoweJ W Hartley

❮ Previous
Next ❯

Citations

Jun 15, 1996·Microscopy Research and Technique·D L VauxI L Weissman
May 1, 1990·Journal of Cellular Physiology·E SchneiderM Dy
Jul 1, 1991·Journal of Cellular Physiology·S L Kirby, S A Bentley
Aug 1, 1995·Journal of Neuroscience Research·Y KonishiT Tabira
Jan 1, 1990·International Journal of Cell Cloning·J N IhleD Askew
Jan 1, 1992·International Journal of Cell Cloning·J R KellerF W Ruscetti
Sep 1, 1992·Cancer Metastasis Reviews·N J McCarthyG T Williams
Mar 1, 1991·The Journal of Membrane Biology·H TanakaY Kurachi
Dec 24, 1986·Journal of Immunological Methods·J Sawada, T Terao
Apr 2, 1987·Journal of Immunological Methods·S N HoD J McKean
Jan 1, 1985·Comparative Immunology, Microbiology and Infectious Diseases·K Bendtzen
Jan 1, 1984·Immunology Letters·Y Y LiuS Dubiski
Apr 1, 1982·European Journal of Cancer & Clinical Oncology·E F Hays, L Hale
Dec 5, 1994·Neuroscience Letters·Y KonishiT Tabira
Jun 1, 1995·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·T TabiraF Gallyas
Jan 1, 1991·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·R DaculsiB Guillemain
Jan 1, 1990·Progress in Growth Factor Research·G R GuyC S Peng
Nov 1, 1989·Cytokine·H J ZiltenerS L McDonald
Jun 1, 2001·Advances in Enzyme Regulation·J A McCubreyS C Pohnert
Jun 1, 2000·Advances in Enzyme Regulation·J A McCubreyW L Blalock
Nov 7, 2000·Experimental Hematology·D J CurtisC G Begley

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.