Growth of microorganisms in total parenteral nutrition solutions without lipid.

International Journal of Medical Sciences
Takashi KuwaharaYoshifumi Inoue

Abstract

To identify the microorganisms that can grow rapidly in total parenteral nutrition (TPN) solutions, we investigated the growth of the major causes of catheter-related blood stream infection (Staphylococcus aureus, Serratia marcescens, Bacillus cereus, and Candida albicans) in TPN solutions without lipid. Experiment 1: A commercial TPN solution without lipid containing multivitamins (pH5.6) was used. A specific number of each test microorganism was added to each 10 mL of the TPN solution and incubated at room temperature. An aliquot of test solution was sampled and inoculated to SCD agar plates at 0, 24, and 48 hrs after the addition of the microorganisms. The number of microorganisms was counted as colony forming units. Experiment 2: The other 2 commercial TPN solutions without lipid (pH5.5) were supplemented with multivitamins. The pH values of the solutions were adjusted to about 6.0, 6.5, or 7.0 using 0.5 mol/L NaOH. The addition of microorganisms, incubation, and counting were performed in the same manner. Experiment 1: S. aureus, S. marcescens, and B. cereus did not increase in the TPN solution without lipid containing multivitamins (pH5.6), but C. albicans increased rapidly. Experiment 2: The 3 bacterial species did not i...Continue Reading

References

Dec 1, 1975·Archives of Surgery·M A MellyW Schaffner
Sep 1, 1986·JPEN. Journal of Parenteral and Enteral Nutrition·M GilbertM F Elmore
Jul 1, 1984·JPEN. Journal of Parenteral and Enteral Nutrition·K S CrockerW P Steffee
Apr 17, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·L A MermelUNKNOWN Society for Healthcare Epidemiology of America
Mar 9, 2002·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·J LlopR Jódar
Jan 28, 2006·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Jane Banton

❮ Previous
Next ❯

Citations

Dec 4, 2012·Nutrients·Walter ZinggMaria Martin
Apr 11, 2014·The Journal of Pediatric Pharmacology and Therapeutics : JPPT : the Official Journal of PPAG·Bethany M DedonatoRyan J Gates
Jul 23, 2013·International Journal of Medical Sciences·Takashi KuwaharaYoshifumi Inoue
Jun 23, 2010·International Journal of Medical Sciences·Takashi KuwaharaYoshifumi Nakashima
Jun 9, 2012·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Peter D AustinMarinos Elia
Mar 7, 2013·Journal of Veterinary Emergency and Critical Care·Isuru GajanayakeDaniel L Chan
Jul 31, 2013·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Peter D AustinMarinos Elia
Apr 15, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Neil GuptaAlexander J Kallen
Feb 24, 2017·BMC Microbiology·Gislaine Aurelie KemegneAugustin Ephrem Nkengfack
May 3, 2013·JPEN. Journal of Parenteral and Enteral Nutrition·Sulieman Abdal RaheemDonald F Kirby
Oct 18, 2011·JPEN. Journal of Parenteral and Enteral Nutrition·Robin S TurpinUNKNOWN IMPROVE Study Group
Jul 22, 2015·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Heather Moulton-MeissnerMatthew Arduino
Jan 10, 2012·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Patricia H Worthington, Karen A Gilbert
Feb 22, 2018·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Pau RieraNoe Garin

❮ Previous
Next ❯

Related Concepts

Related Feeds

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.