Growth of the stress-bearing and shape-maintaining murein sacculus of Escherichia coli.

Microbiology and Molecular Biology Reviews : MMBR
J V Höltje

Abstract

To withstand the high intracellular pressure, the cell wall of most bacteria is stabilized by a unique cross-linked biopolymer called murein or peptidoglycan. It is made of glycan strands [poly-(GlcNAc-MurNAc)], which are linked by short peptides to form a covalently closed net. Completely surrounding the cell, the murein represents a kind of bacterial exoskeleton known as the murein sacculus. Not only does the sacculus endow bacteria with mechanical stability, but in addition it maintains the specific shape of the cell. Enlargement and division of the murein sacculus is a prerequisite for growth of the bacterium. Two groups of enzymes, hydrolases and synthases, have to cooperate to allow the insertion of new subunits into the murein net. The action of these enzymes must be well coordinated to guarantee growth of the stress-bearing sacculus without risking bacteriolysis. Protein-protein interaction studies suggest that this is accomplished by the formation of a multienzyme complex, a murein-synthesizing machinery combining murein hydrolases and synthases. Enlargement of both the multilayered murein of gram-positive and the thin, single-layered murein of gram-negative bacteria seems to follow an inside-to-outside growth strategy...Continue Reading

References

Dec 1, 1975·Journal of Bacteriology·J V HöltjeU Schwarz
Feb 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·H SuzukiY Hirota
Nov 1, 1978·Journal of Bacteriology·R W VerwerU Schwarz
Sep 1, 1979·Journal of Bacteriology·W Keck, U Schwarz
Jan 1, 1976·International Review of Cytology·P GiesbrechtB Reinicke
Feb 1, 1975·Journal of General Microbiology·E W Goodell, U Schwarz
Oct 15, 1975·European Journal of Biochemistry·J van HeijenoortY van Heijenoort
Aug 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·B G Spratt
Sep 1, 1992·Journal of Bacteriology·M CaparrósM A de Pedro
Jan 1, 1991·Annual Review of Microbiology·J M Ghuysen
Sep 1, 1991·Journal of Bacteriology·B Walderich, J V Höltje
Dec 1, 1991·Journal of Bacteriology·F B WientjesN Nanninga
Jun 1, 1991·Journal of Bacteriology·U Kohlrausch, J V Höltje
Jan 1, 1990·Annual Review of Genetics·P A de BoerL I Rothfield
Jan 1, 1990·Research in Microbiology·M MatsuhashiF Ishino
Jan 1, 1990·Research in Microbiology·N NanningaC L Woldringh
Jul 1, 1989·Journal of Bacteriology·R Prats, M A de Pedro
Aug 1, 1988·Journal of Bacteriology·S CooperB Guenther

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Citations

Jul 27, 2000·Journal of Bacteriology·J Meador-Parton, D L Popham
Aug 31, 2000·Applied and Environmental Microbiology·A L Koch
May 10, 2001·Journal of Bacteriology·S R Lybarger, J R Maddock
Sep 15, 2001·Antimicrobial Agents and Chemotherapy·A L Koch
Dec 14, 2001·Journal of Bacteriology·Stéphane Mesnage, Agnès Fouet
Jun 12, 2002·Journal of Bacteriology·Xavier CharpentierJean-Michel Masson
Mar 3, 2021·Journal of Bacteriology·Sandra SanchezDaniel B Kearns
Jul 21, 2010·Journal of Bacteriology·Allison M Michaelis, Zemer Gitai
Oct 15, 2003·Clinical Microbiology Reviews·Arthur L Koch
Jan 21, 2021·EcoSal Plus·Shambhavi GardeManjula Reddy
Dec 1, 2011·Microbiology and Molecular Biology Reviews : MMBR·Sean X Sun, Hongyuan Jiang
Dec 1, 2011·Microbiology and Molecular Biology Reviews : MMBR·Jean van Heijenoort
Aug 3, 2002·European Journal of Biochemistry·Gary T JenningsGuido Grandi
Mar 7, 2008·Microbiology and Molecular Biology Reviews : MMBR·Erik C Hett, Eric J Rubin
Apr 30, 2021·IScience·Lillian ZhuKerwyn Casey Huang
Jun 7, 2008·Microbiology and Molecular Biology Reviews : MMBR·James T Park, Tsuyoshi Uehara
Aug 1, 2018·Journal of Bacteriology·Mariela García-RamosGeorges Dreyfus
Jun 21, 2011·Journal of Bacteriology·Adrian D Land, Malcolm E Winkler
Oct 18, 2011·Journal of Bacteriology·Silvia M González-LeizaJuan A Ayala
Dec 13, 2006·Microbiology and Molecular Biology Reviews : MMBR·Rut Carballido-López
Aug 6, 2020·MBio·Spencer CesarKerwyn Casey Huang
Nov 20, 2002·Research in Microbiology·Thomas G BernhardtRy Young
Dec 5, 2009·Journal of the American Chemical Society·Tania J LupoliDaniel E Kahne

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Bacterial Cell Wall Structure (ASM)

Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Here is the latest research on bacterial cell wall structures.

Bacterial Cell Wall Structure

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