GSK3 modulation in acute lung injury, myocarditis and polycystic kidney disease-related aneurysm

Biochimica Et Biophysica Acta. Molecular Cell Research
Wei-Lun LiuHeng-Liang Lin

Abstract

GSK3 are involved in different physical and pathological conditions and inflammatory regulated by macrophages contribute to significant mechanism. Infection stimuli may modulate GSK3 activity and influence host cell adaption, immune cells infiltration or cytokine expressions. To further address the role of GSK3 modulation in macrophages, the signal transduction of three major organs challenged by endotoxin, virus and genetic inherited factors are briefly introduced (lung injury, myocarditis and autosomal dominant polycystic kidney disease). As a result of pro-inflammatory and anti-inflammatory functions of GSK3 in different microenvironments and stages of macrophages (M1/M2), the rational resolution should be considered by adequately GSK3.

References

Aug 1, 1975·The Journal of Experimental Medicine·Z Werb, S Gordon
Apr 1, 1995·Journal of the American College of Cardiology·K OhtaniT Kamada
Aug 1, 1997·Journal of the American Society of Nephrology : JASN·A B ChapmanR W Schrier
Dec 18, 1998·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·A BardajíJ A Oliver
Aug 24, 1999·Molecular and Cellular Biology·K A SheppardT Collins
Oct 20, 1999·Virchows Archiv : an International Journal of Pathology·K NittaM Nagata
Jul 8, 2000·Kidney International·L BarisoniP Mundel
Dec 12, 2001·Kidney International·K HiromuraS J Shankland
Apr 13, 2002·Current Molecular Medicine·Peter J Roach
Mar 5, 2003·Journal of Cell Science·Bradley W Doble, James R Woodgett
Dec 25, 2003·Journal of the American Society of Nephrology : JASN·Marcus J MoellerLawrence B Holzman
Jul 30, 2004·Molecular and Cellular Biology·Bartholomew A PedersonPeter J Roach
Dec 8, 2004·Current Pharmaceutical Design·Paul E Marik
Jan 18, 2005·Cell·Takeshi YoshimuraKozo Kaibuchi
Sep 17, 2005·Molecular and Cellular Biology·Kris A SteinbrecherAlbert S Baldwin
Jan 26, 2006·American Journal of Physiology. Renal Physiology·Birgitte Mønster ChristensenSøren Nielsen
Feb 9, 2006·Neurobiology of Aging·Patrizia De SarnoRichard S Jope
Jun 2, 2006·Journal of the American Society of Nephrology : JASN·Marcello TonelliAmit X Garg
Sep 1, 2006·Journal of the American Society of Nephrology : JASN·Chun-Liang LinFeng-Sheng Wang
Apr 17, 2007·Lancet·Vicente E TorresYves Pirson
Jun 22, 2007·Journal of the American Society of Nephrology : JASN·Sandro RossettiUNKNOWN CRISP Consortium
Oct 3, 2007·Cell Metabolism·Katrina MacAulayJames R Woodgett

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BETA
biopsy
nuclear translocation

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