Sep 29, 1999

Guaianolides from Centaurea nicolai: antifungal activity

Phytochemistry
V VajsS Milosavljević

Abstract

A new guaianolide, 3-deacetyl-9-O-acetylsalograviolide A, along with four known closely related lactones, salograviolide A, 9-O-acetylsalograviolide A, kandavanolide and salograviolide B were detected in the aerial parts of the flowering plant Centaurea nicolai. Antifungal tests performed on salograviolide A and its 9-O-acetyl and 3-O-deacetyl-9-O-acetyl derivatives revealed inhibitory activity against Aspergillus niger, A. ochraceus, Penicillium ochrochloron, Cladosporium cladosporoides, Fusarium tricinctum and Phomopsis helianthi. Neither of them was active against Trichoderma viride.

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Mentioned in this Paper

In Vivo NMR Spectroscopy
Derivatives
Trichoderma viride antigen
Antibiotics, Antifungal
Fusarium tricintum
Amphiporus ochraceus
Filamentous fungus
Alophoixus ochraceus
Sphaeranthus
Sesquiterpenes

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