Guanethidine/dipivefrin and pilocarpine in the treatment of increased intraocular pressure

Klinische Monatsblätter für Augenheilkunde
M OberD Dausch


Thirty patients with ocular hypertension or open-angle glaucoma were tested to see if, and to what extent, guanethidine/dipivefrin and pilocarpine produced a supplementary reduction in intraocular pressure. An equally marked additional lowering of pressure was achieved when patients who had been given guanethidine/dipivefrin over an extended period of time were additionally treated with one dose of pilocarpine 2%. The reduction in intraocular pressure was much more pronounced in patients who had been treated with pilocarpine 2% alone over an extended period of time, followed by a single dose of guanethidine/dipivefrin, than in those who had been treated first with guanethidine/dipivefrin and subsequently with pilocarpine.

Related Concepts

Glaucoma, Open-Angle
Guanethidine Sulfate (2: 1), 14C-Labeled
Physiologic Intraocular Pressure
Ocular Hypertension

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