Guidance for the practical management of warfarin therapy in the treatment of venous thromboembolism

Journal of Thrombosis and Thrombolysis
Daniel M WittJack E Ansell

Abstract

Venous thromboembolism (VTE) is a serious and often fatal medical condition with an increasing incidence. The treatment of VTE is undergoing tremendous changes with the introduction of the new direct oral anticoagulants and clinicians need to understand new treatment paradigms. This article, initiated by the Anticoagulation Forum, provides clinical guidance based on existing guidelines and consensus expert opinion where guidelines are lacking. Well-managed warfarin therapy remains an important anticoagulant option and it is hoped that anticoagulation providers will find the guidance contained in this article increases their ability to achieve optimal outcomes for their patients with VTE Pivotal practical questions pertaining to this topic were developed by consensus of the authors and were derived from evidence-based consensus statements whenever possible. The medical literature was reviewed and summarized using guidance statements that reflect the consensus opinion(s) of all authors and the endorsement of the Anticoagulation Forum's Board of Directors. In an effort to provide practical and implementable information about VTE and its treatment, guidance statements pertaining to choosing good candidates for warfarin therapy, war...Continue Reading

References

Jul 11, 2003·The New England Journal of Medicine·Agnes Y Y LeeUNKNOWN Randomized Comparison of Low-Molecular-Weight Heparin versus Oral Anticoagulant Therapy for the Prevention of Recurrent Veno
Oct 19, 2004·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
Apr 2, 2005·British Journal of Haematology·Gualtiero PalaretiUNKNOWN ad hoc Study Group of the Italian Federation of Anticoagulation Clinics*
May 25, 2005·Archives of Internal Medicine·Anne M HolbrookPhilip S Wells
Aug 30, 2006·British Journal of Haematology·Sue JowettDavid Fitzmaurice
Aug 2, 2007·Journal of Thrombosis and Haemostasis : JTH·E K RomboutsF J M Van Der Meer
Jan 17, 2008·Chest·Samuel G JohnsonDaniel M Witt
Mar 11, 2008·Journal of Thrombosis and Thrombolysis·Nathan P ClarkRobert McDuffie
May 21, 2008·Journal of Thrombosis and Haemostasis : JTH·L PollerJ Jespersen
Jun 19, 2008·The Annals of Pharmacotherapy·David A GarciaUNKNOWN Anticoagulation Forum
Jul 29, 2008·Pharmacotherapy·Nathan P ClarkUNKNOWN Warfarin-Associated Research Projects and Other Endeavors Consortium
Jun 17, 2009·Circulation·P Michael HoJohn S Rumsfeld
Jun 30, 2009·Current Opinion in Pulmonary Medicine·Keattiyoat Wattanakit, Mary Cushman
Jul 28, 2009·Journal of Thrombosis and Haemostasis : JTH·M A Crowther, T E Warkentin
Oct 3, 2009·Journal of Travel Medicine·Michael Schwartz
Dec 8, 2009·The New England Journal of Medicine·Sam SchulmanUNKNOWN RE-COVER Study Group
Sep 14, 2010·Journal of Thrombosis and Haemostasis : JTH·S SaokaewA Sukonthasarn
Nov 13, 2010·Drug Metabolism and Disposition : the Biological Fate of Chemicals·Lifei WangDonglu Zhang
Dec 7, 2010·The New England Journal of Medicine·Rupert BauersachsSebastian Schellong
Jan 15, 2011·Expert Opinion on Pharmacotherapy·Joyce Hs You
Apr 21, 2011·Circulation. Cardiovascular Quality and Outcomes·Adam J RoseAl Ozonoff
Aug 13, 2011·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·Jessica SchilligJames S Kalus
Aug 30, 2011·Journal of Managed Care Pharmacy : JMCP·Megan E KleinowPeter Whittaker
Oct 4, 2011·Journal of Thrombosis and Thrombolysis·Carol MotyckaKelly Jones

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Citations

Apr 1, 2017·International Journal of Clinical Pharmacy·Brian T CryderRami Rihani
Feb 27, 2018·Journal of Thrombosis and Thrombolysis·Jeremy W Vandiver, K Diane Beavers
Dec 23, 2016·Physiological Reports·Kohei TatsumiNigel Mackman
Apr 21, 2018·Pharmacy : Journal of Pharmacy, Education and Practice·Emily M Hawes
Oct 28, 2018·International Journal of Clinical Pharmacy·Xiaotong XiaJinhua Zhang
Jan 26, 2018·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Dennis S GuadarramaJoseph D Sweeney
Sep 4, 2020·The Oncologist·Evan C ChenJean M Connors
Dec 14, 2018·Journal of Pharmacy Practice·Samantha M VogelEvan J Peterson
Jun 8, 2018·Frontiers in Pharmacology·Letícia C TavaresPaulo C J L Santos
Jan 18, 2019·Medicine·Pablo Demelo-RodríguezJorge Del Toro-Cervera
Apr 20, 2018·Nature Reviews. Disease Primers·Angel LanasJoseph J Y Sung
Jul 28, 2018·European Journal of Clinical Pharmacology·Letícia C TavaresPaulo Caleb Junior Lima Santos
Jun 13, 2020·The Journal of Applied Laboratory Medicine·Junhua ZhangFei Xiao
Mar 9, 2021·Journal of Pharmacy & Bioallied Sciences·Sireen Abdul Rahim Shilbayeh
Jun 1, 2021·Critical Care Clinics·David B Liss, Michael E Mullins
Mar 25, 2021·The Journal of Applied Laboratory Medicine·Lauren N PearsonRobert L Schmidt
Jul 2, 2021·Clinical Case Reports·Negin YavariSeyed Hossein Ahmadi Tafti
Oct 15, 2021·Circulation Journal : Official Journal of the Japanese Circulation Society·Nobuhiro HaraTakashi Ashikaga
Oct 22, 2021·Thrombosis Research·Aubrey E JonesDaniel M Witt

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