Guide to Enhancing Swallowing Initiation: Insights from Findings in Healthy Subjects and Dysphagic Patients

Current Physical Medicine and Rehabilitation Reports
Kensuke YamamuraKeiichiro Okamoto

Abstract

Difficulty in initiating swallowing is one of the main symptoms of oropharyngeal dysphagia. Therefore, enhancing swallowing initiation is an important approach for the treatment of oropharyngeal dysphagia. This review aims to introduce recent approaches to enhancing swallowing and to discuss their therapeutic potential. Both central interventions such as non-invasive brain stimulation and peripheral interventions such as electrical stimulation to peripheral tissues are conducted to enhance swallowing. Recent studies have paid more attention to generating neuroplasticity to produce long-lasting facilitative effect on swallowing. Transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), pharyngeal electrical stimulation (PES), transcutaneous electrical stimulation, and somatic and chemical stimulation were introduced. Considerable evidence supports the therapeutic potential of TMS and PES. Other approaches need further studies to verify their efficacy (e.g., duration of the effect and a limit of effectiveness) and/or possible risk of adverse effects.

References

Sep 28, 1979·Brain Research·A WeerasuriyaC H Hockman
Jan 1, 1982·Physiological Reviews·A J Miller
Sep 14, 1999·Journal of Neurophysiology·R E MartinB J Sessle
Mar 16, 2000·The American Journal of Medicine·Y YoshidaT Nakashima
Apr 18, 2002·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Jun-Ichi KitagawaYoshiaki Yamada
May 24, 2003·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·S BroadleyP D Thompson
Dec 4, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Cumhur Ertekin, Ibrahim Aydogdu
Sep 1, 1996·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·S K DanielsM A Sullivan
Jan 9, 2009·Dysphagia·Ruth E Martin
Apr 17, 2009·Current Opinion in Otolaryngology & Head and Neck Surgery·Emilia Michou, Shaheen Hamdy
Sep 4, 2010·Dysphagia·Catriona M Steele, Arthur J Miller
Mar 29, 2011·Stroke; a Journal of Cerebral Circulation·Sandeep KumarGottfried Schlaug
Apr 2, 2011·The Journal of Comparative Neurology·Yoichiro SugiyamaYasuo Hisa
Dec 12, 2012·Archives of Physical Medicine and Rehabilitation·Julie A TheurerRuth E Martin
Feb 9, 2013·Neurorehabilitation and Neural Repair·Takashi ShigematsuKikuo Ohno
Dec 7, 2013·Progress in Brain Research·Seth A HaysMichael P Kilgard
Dec 21, 2013·Folia Phoniatrica Et Logopaedica : Official Organ of the International Association of Logopedics and Phoniatrics (IALP)·Simone MillerMartin Ptok
Jan 11, 2014·CoDAS·Ana Rita GattoMaria Aparecida Coelho de Arruda Henry
May 28, 2015·Brain Research Bulletin·Yoshihide SatohMakoto Inoue

❮ Previous
Next ❯

Citations

Nov 14, 2019·Journal of Clinical Medicine·Emilie ReberZeno Stanga
Nov 10, 2018·Journal of Applied Physiology·Yacine OuahchiEric Verin

❮ Previous
Next ❯

Methods Mentioned

BETA
imaging techniques

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.