Guided bone tissue elaboration by osteogenic cells in vitro

Journal of Biomedical Materials Research
K Gomi, J E Davies

Abstract

Primary rat bone marrow cells were cultured for 2 weeks in polystyrene dishes whose surfaces had been roughened using 600- or 320-grit silicon carbide paper. Eight samples were prepared of each of the three groups of dishes, to include a nontreated control surface. Following the culture period, the dishes were stained by von Kossa's method. The distribution of bone formed during the culture period was examined by light microscopy and the area of bone formed quantified. Results demonstrated that both the amount and spatial distribution of bone were influenced by the roughness of the underlying substratum. Differences between the smooth and roughened surfaces were statistically different at P < .05.

References

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Citations

Nov 1, 1996·Journal of Biomedical Materials Research·H OhgushiT Shibuya
Oct 23, 1997·Journal of Biomedical Materials Research·C LotyJ M Sautier
Apr 29, 1998·Journal of Biomedical Materials Research·S H MaxianJ P Zawadsky
Jan 26, 2002·Computer Methods and Programs in Biomedicine·Wei Sun, Pallavi Lal
Jul 17, 2004·Annual Review of Biomedical Engineering·G Vunjak-NovakovicDavid L Kaplan
Mar 22, 2008·Journal of Biomedical Materials Research. Part a·Rosemeire de Lordo FrancoAdalberto Luiz Rosa
Jun 5, 2008·Journal of Biomedical Materials Research. Part a·Chaoyuan WangHala Zreiqat
Nov 30, 2006·Proceedings of the National Academy of Sciences of the United States of America·Danyan XuNipavan Chiamvimonvat
Dec 14, 2011·Biomedical Materials·Rajeswari RavichandranCasey K Chan
Feb 14, 2019·International Journal of Molecular Sciences·Saturnino Marco LupiRuggero Rodriguez Y Baena

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