Guided tissue regeneration/deproteinized bovine bone mineral or papilla preservation flaps alone for treatment of intrabony defects. II: radiographic predictors and outcomes

Journal of Clinical Periodontology
Antonio LiñaresEuropean Research Group on Periodontology (ErgoPerio)

Abstract

This study reports the secondary analysis of a randomized-controlled clinical trial designed to assess the efficacy of deproteinized bovine mineral and a collagen membrane in the treatment of intrabony defects. The specific aims of this report are (1) to analyse the radiographic bone changes 1 year after therapy and (2) to assess the association between radiographic defect angle and treatment outcomes. Baseline and 12-month radiographs were collected from 120 patients with advanced chronic periodontitis from 10 centres in seven countries as part of a multi-centre clinical trial. All patients had at least one intrabony defect > or =3 mm in depth. The treatment consisted of simplified or modified papilla preservation flaps to access the defect. After debridement of the area, a deproteinized bovine mineral and a collagen membrane were applied in the test subjects, and omitted in the controls. Main outcome measures were radiographic bone fill and defect resolution 1 year after surgery. One hundred and twenty pairs of radiographs were obtained, of which 110 pairs were measurable (57 tests and 53 controls). One year after treatment, radiographic resolution of the intrabony component was significantly higher in the test group (3.2+/-1...Continue Reading

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Citations

Mar 5, 2008·Journal of Periodontology·Giovanni Zucchelli, Massimo De Sanctis
Apr 14, 2015·Periodontology 2000·Pierpaolo Cortellini, Maurizio S Tonetti
Sep 10, 2009·Australian Dental Journal·S Ivanovski
Nov 10, 2006·Journal of Clinical Periodontology·Ivan BokanUlrich Schlagenhauf
Oct 16, 2007·Journal of Clinical Periodontology·Christer SlotteDan Lundgren
Nov 19, 2010·European Journal of Oral Sciences·Yu-Kang TuLuigi Nibali
May 13, 2011·Clinical Oral Implants Research·Nikos MardasNikolaos Donos
Mar 18, 2017·Journal of Clinical Periodontology·Frank BröselerSøren Jepsen
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May 18, 2019·Journal of Periodontal & Implant Science·Soram OhJi-Young Han
Nov 9, 2018·Journal of Periodontal & Implant Science·SunJin HeoJeomil Choi
Oct 8, 2020·Journal of Clinical Periodontology·Luigi NibaliMaurizio Tonetti
Mar 9, 2021·Journal of Oral Biosciences·Muhammad Saad ShaikhYasser Riaz Malik
Nov 18, 2021·Journal of Periodontal Research·Vasiliki P KoidouNikolaos Donos
Jan 13, 2022·Clinical and Experimental Dental Research·Knut AdamIngmar Staufenbiel

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