Guideline-Directed Medication Use in Patients With Heart Failure With Reduced Ejection Fraction in India: American College of Cardiology's PINNACLE India Quality Improvement Program

Clinical Cardiology
Yashashwi PokharelSalim S Virani

Abstract

Little is known about the use of guideline-directed medical therapy (GDMT) in outpatients with heart failure with reduced left ventricular ejection fraction (HFrEF; ≤40%) in India. Our objective was to understand the use of GDMT in outpatients with HFrEF in India. The Practice Innovation And Clinical Excellence (PINNACLE) India Quality Improvement Program (PIQIP) is a registry for cardiovascular quality improvement in India supported by the American College of Cardiology Foundation. Between January 2008 and September 2014, we evaluated documentation of use of angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin receptor blockers (ARBs) and β-blockers, or both, among outpatients with HFrEF seeking care in 10 centers enrolled in the PIQIP registry. Among 75 639 patients in the PIQIP registry, 34 995 had EF reported, and 15 870 had an EF ≤40%. The mean age was 56 years; 23% were female. Hypertension, diabetes, coronary artery disease, and myocardial infarction were present in 37%, 23%, 27%, and 17%, respectively. Use of ACEIs/ARBs, β-blockers, and both were documented in 33.5%, 34.9%, and 29.6% of patients, respectively. The documentation of GDMT was higher in men, in patients age ≥65 years, and in those with presence of h...Continue Reading

References

Aug 14, 2010·Journal of the American College of Cardiology·Anthony N DeMaria
Apr 20, 2013·Current Cardiology Reviews·Harikrishnan Sivadasan Pillai, Sanjay Ganapathi
Jun 7, 2013·Circulation·UNKNOWN WRITING COMMITTEE MEMBERSUNKNOWN American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
Jun 12, 2013·Journal of the American College of Cardiology·Clyde W YancyUNKNOWN American Heart Association Task Force on Practice Guidelines
Jan 9, 2014·International Journal of Cardiology·Christopher CookDarrel P Francis
May 27, 2015·European Journal of Heart Failure·Sivadasanpillai HarikrishnanUNKNOWN Trivandrum Heart Failure Registry

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Citations

Jan 17, 2020·Expert Review of Cardiovascular Therapy·Dhruv MahttaSalim S Virani
Aug 25, 2020·The Egyptian Heart Journal : (EHJ) : Official Bulletin of the Egyptian Society of Cardiology·Jeeva JosephJabir Abdullakutty
Apr 19, 2017·Current Atherosclerosis Reports·Ankur KalraSalim S Virani

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