Guidelines for the descriptive presentation and statistical analysis of contact allergy data

Contact Dermatitis
Wolfgang UterOlaf Gefeller

Abstract

The present guidelines aim to support clinical researchers in adequately presenting data on contact allergy, and to use statistical tests appropriate for their data. A description of the mode of selection of patients, and of their relevant demographic details, is an essential prerequisite for the correct interpretation of study results. Proportions and rates, if regarded as estimate of these parameters of a target populations, should normally be supplemented with confidence intervals to address precision. Concordance, i.e., agreement between two ratings in a dependent sample, must be quantified with a chance-corrected measure such as Cohen's kappa coefficient. If the diagnostic quality of an outcome is being assessed, standard measures like sensitivity and specificity, as well as the prevalence-dependent positive and negative predictive values should be calculated. Often, contact allergy to a certain substance depends on several factors. In this situation, depending on the research question, techniques like stratification, standardization or multifactorial analysis should be employed. With increasing complexity of statistical description and analysis, consulting with a biostatistician is often mandatory.

References

Jan 1, 1992·Contact Dermatitis·H A SmitJ P Nater
Dec 1, 1991·Statistics in Medicine·D G Altman
Jan 1, 1988·Journal of Clinical Epidemiology·W D Thompson, S D Walter
Feb 1, 1985·Contact Dermatitis·K E Andersen, N K Veien
Apr 1, 1980·Contact Dermatitis·A Dooms-GoossensH Degreef
Sep 24, 1998·Contact Dermatitis·J D JohansenT Menné
Feb 19, 1999·Journal of Epidemiology and Community Health·C Poole, K J Rothman
Jun 29, 2000·Archives of Dermatology·C Charman, H Williams
Apr 9, 2002·Cancer Causes & Control : CCC·Freddie BrayDonald M Parkin
Nov 25, 2003·The British Journal of Dermatology·D A BuckleyJ P McFadden
Aug 11, 2007·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·A SchnuchUNKNOWN Deutschen Dermatologischen Gesellschaft (DDG) zur Durchführung des Epikutantests mit Kontaktallergenen

❮ Previous
Next ❯

Citations

Nov 12, 2005·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·M WormA Schnuch
Dec 23, 2008·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·A SchnuchUNKNOWN IVDK
Sep 9, 2011·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·J GeierA Schnuch
Dec 31, 2009·International Archives of Occupational and Environmental Health·Wolfgang UterOlaf Gefeller
Sep 25, 2010·International Archives of Occupational and Environmental Health·Johannes GeierAxel Schnuch
Sep 14, 2013·Dermatitis : Contact, Atopic, Occupational, Drug·Erin M WarshawFrances J Storrs
Mar 12, 2013·Dermatitis : Contact, Atopic, Occupational, Drug·Erin M WarshawHoward I Maibach
Jan 24, 2013·Dermatitis : Contact, Atopic, Occupational, Drug·Peter C SchalockChristen Mowad
Jan 13, 2016·Contact Dermatitis·Wolfgang UterJeanne Duus Johansen
May 22, 2009·Actas dermo-sifiliográficas·M T Bordel-Gómez, A Miranda-Romero
May 10, 2005·Pharmacoepidemiology and Drug Safety·C A Menezes de PáduaW Uter
May 31, 2008·The British Journal of Dermatology·A SchnuchW Uter
Sep 3, 2008·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Wolfgang UterHolger Lessmann
Sep 9, 2006·Contact Dermatitis·Lilach ZollerSara Weltfriend
Nov 3, 2007·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Wolfgang UterAxel Schnuch
Apr 3, 2008·Pharmacoepidemiology and Drug Safety·C A Menezes de PáduaW Uter
May 3, 2008·Journal of the European Academy of Dermatology and Venereology : JEADV·U JappeW Uter
Jan 27, 2006·Allergy·J BraschUNKNOWN German Contact Dermatitis Research Group (DKG) and the Information Network of Departments of Dermatology (IVDK)
Jul 16, 2008·Journal of the European Academy of Dermatology and Venereology : JEADV·M T Bordel-GómezJ Castrodeza-Sanz
Apr 20, 2007·Contact Dermatitis·Wolfgang UterUNKNOWN Information Network of Departments of Dermatology
Jul 23, 2013·Contact Dermatitis·Wolfgang UterOlaf Gefeller
May 4, 2011·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Heinrich DickelJochen Brasch
May 12, 2010·Journal of the European Academy of Dermatology and Venereology : JEADV·A BeliauskieneA Schnuch
Apr 11, 2012·Contact Dermatitis·Wolfgang UterAxel Schnuch
Sep 14, 2013·Contact Dermatitis·Axel Schnuch, Judith Schwitulla
Nov 3, 2010·Contact Dermatitis·Jochen BraschUNKNOWN German Contact Dermatitis Group (DKG)
Oct 16, 2010·Contact Dermatitis·Andrea KrautheimJohannes Geier
Feb 22, 2011·The British Journal of Dermatology·A SchnuchW Uter
Dec 14, 2011·Contact Dermatitis·Oliver Kuss, Andreas Stang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.