PMID: 9547898Apr 21, 1998Paper

Guidelines for the interpretation of analytical toxicology results and unit of measurement conversion factors

Annals of Clinical Biochemistry
R J Flanagan

Abstract

A data compilation has been published on the World Wide Web [http:// www.leeds.ac.uk/acb/annals] which aims to assist in the interpretation of analytical toxicology results in individual patients. 'Therapeutic' or 'normal' plasma/whole blood/urine concentrations, as well as the concentrations associated with serious toxicity (if known), for some 700 analytes of toxicological interest are given together with (when possible) relative atomic or formula masses, and mass/amount and amount/mass concentration conversion factors. This paper gives background and supplementary information which should be borne in mind when providing interpretation or using the Web table. Supplementary tables listing (i) common therapeutic drug monitoring assays and guidelines for interpretation of results, (ii) emergency toxicology analyses which may influence active treatment, (iii) blood carboxyhaemoglobin saturation and clinical features of toxicity, (iv) information important when interpreting the results of toxicology investigations, (v) factors which may affect interpretation of analytical toxicology results, and (vi) conversion factors for volatile compounds are included.

References

Jul 1, 1983·Human Toxicology·A H Stead, A C Moffat
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Citations

Jun 27, 2008·International Journal of Legal Medicine·L FantonD Malicier
Feb 22, 2011·International Journal of Legal Medicine·Fabien BévalotLaurent Fanton
Feb 13, 2013·International Journal of Legal Medicine·F BévalotD Malicier
Dec 3, 2014·Colloids and Surfaces. B, Biointerfaces·N VargaI Dékány
Feb 7, 2008·Environmental Geochemistry and Health·S RapantM Letkovicová
May 12, 2009·Naunyn-Schmiedeberg's Archives of Pharmacology·Markéta BébarováJirí Simurda
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Mar 10, 2016·Forensic Science International : Synergy·E Le GarffG Tournel
Feb 1, 2005·Basic & Clinical Pharmacology & Toxicology·Won-Ho Shin, Eun-Joo Kim
Oct 18, 2005·Forensic Science International : Synergy·Brice M R AppenzellerRobert Wennig
Oct 19, 2006·European Journal of Pharmacology·Markéta BébarováMarie Nováková
Jul 27, 2005·Toxicological Reviews·Robert J Flanagan, Geraldine Connally
Jan 11, 2007·Journal of Forensic Sciences·Laurent FantonDaniel Malicier
Oct 12, 2002·American Journal of Physiology. Lung Cellular and Molecular Physiology·Christophe FaisyCharles Advenier
Jul 22, 2006·Clinical Chemistry·François-Ludovic SauvagePierre Marquet
Mar 8, 2020·International Journal of Legal Medicine·Jean-François WiartJean-Michel Gaulier
Jul 17, 2004·Therapeutic Drug Monitoring·Alan Wayne Jones, Helena Larsson
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Apr 20, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·M MelilloS V Mikhalovsky

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