Guillain-Barré syndrome (demyelinating) six weeks after bariatric surgery: A case report and literature review

Obesity Research & Clinical Practice
Noman IshaqueMuhammad Wasay

Abstract

Obesity is a major health problem worldwide. Bariatric surgery has been increasingly used to manage obesity. Many acute as well as chronic neurological complications have been reported after bariatric surgery including Guillain-Barré syndrome (GBS). An autoimmune process has been postulated as the underlying pathophysiology. Most of the reported cases of GBS after bariatric surgery are of the axonal variety. Here, we report a case of a demyelinating variety of GBS in a young woman who presented with acute onset of progressive weakness and paresthesia of all limbs within six weeks after bariatric surgery. She was treated with intravenous immunoglobulin (IVIG) and rehabilitation. She had complete recovery on follow-up. We believe that onset of acute inflammatory demyelinating polyradiculoneuropathy (AIDP), which is demyelinating variety of GBS, is associated with changes in immune system after bariatric surgery.

References

Aug 27, 2002·Obesity Surgery·Craig G ChangMarilyn M Rymer
Oct 27, 2004·Neurology·P ThaisetthawatkulP J B Dyck
Jun 24, 2005·Muscle & Nerve·Boyd M KoffmanNoor A Pirzada
Nov 23, 2006·Arquivos de neuro-psiquiatria·Flavia Costa Nunes MachadoSílvia Mazzali-Verst
May 2, 2012·International Journal of Obesity : Journal of the International Association for the Study of Obesity·R Huttunen, J Syrjänen
Jan 23, 2013·Obesity Surgery·Henry Buchwald, Danette M Oien
Jun 11, 2014·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Anne F Landais
Jul 26, 2014·Obesity Surgery·Anne Landais

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Citations

Oct 27, 2015·Current Neurology and Neuroscience Reports·Jerry Clay Goodman
Jan 24, 2019·Case Reports in Surgery·Alana H SunbolMohammed Nassif
Dec 29, 2020·Neuroscience Letters·Kathryn R MossAhmet Höke
Nov 27, 2020·Frontiers in Neurology·Chuxin HuangWei Lu
May 22, 2021·Journal of Clinical Neuromuscular Disease·Najwa Al-Bustani, Zulfiqar Hussein
Aug 5, 2021·Endocrinología, Diabetes Y Nutrición·Laura Hernández-MontoliuNúria Vilarrasa

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