Gut microbiota of the European Brown Hare (Lepus europaeus)

Scientific Reports
G L StalderE Mann

Abstract

Diseases of the gastrointestinal tract due to changes in the bacterial flora have been described with increasing incidence in the European brown hare. Despite extensive demographic and phylogeographic research, little is known about the composition of its gut microbiota and how it might vary based on potential environmental or host factors. We analysed the intestinal and faecal microbiota of 3 hare populations by Illumina MiSeq 16S rRNA gene amplicon sequencing. The phyla and OTU abundance composition differed significantly between intestinal and faecal samples (PERMANOVA: P = 0.002 and P = 0.031, respectively), but in both sample types Firmicutes and Bacteroidetes dominated the microbial community composition (45.51% and 19.30% relative abundance). Intestinal samples contained an enrichment of Proteobacteria compared with faecal samples (15.71-fold change, P < 0.001). At OTU level, a significant enrichment with best BLAST hits to the Escherichia-Shigella group, Eubacterium limosum, Sphingomonas kyeonggiensis, Flintibacter butyricus and Blautia faecis were detected in intestinal samples (P < 0.05). In our statistical model, geographic location and possibly associated environmental factors had a greater impact on the microbiota ...Continue Reading

References

May 18, 1999·Reproduction, Nutrition, Development·M T PadilhaB Carré
Feb 25, 2005·FEMS Microbiology Letters·Leticia AbeciaNeil R McEwan
Dec 8, 2005·Applied and Environmental Microbiology·Catherine Lozupone, Rob Knight
Jan 20, 2007·Science·S J ButlerK Norris
Jun 26, 2007·Applied and Environmental Microbiology·Qiong WangJames R Cole
Oct 19, 2007·Nature·Peter J TurnbaughJeffrey I Gordon
Feb 6, 2008·PLoS Pathogens·Philip McKennaFrederic D Bushman
May 24, 2008·Science·Ruth E LeyJeffrey I Gordon
Oct 13, 2009·Genome Research·UNKNOWN NIH HMP Working GroupMark Guyer
Apr 13, 2010·Nature Methods·J Gregory CaporasoRob Knight
Aug 17, 2010·Bioinformatics·Robert C Edgar
Dec 7, 2010·ILAR Journal·Alexis GarcíaThomas E Besser
Dec 21, 2010·Nature Immunology·Kendle M Maslowski, Charles R Mackay
Feb 18, 2011·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·F D PopescuT Ruf
Mar 15, 2011·International Journal of Systematic and Evolutionary Microbiology·Kirsti M RitalahtiFrank E Löffler
Jun 11, 2011·Veterinary Microbiology·Hyeun Bum KimRichard E Isaacson
Mar 24, 2012·Animal : an International Journal of Animal Bioscience·R J MichellandL Fortun-Lamothe
Mar 27, 2012·Conservation Biology : the Journal of the Society for Conservation Biology·Kent H RedfordDenise McAloose
May 5, 2012·PloS One·Floyd E DewhirstZoe V Marshall-Jones
Feb 9, 2013·Veterinary Microbiology·Alton G SwennesJames G Fox
Jun 19, 2013·Animal : an International Journal of Animal Bioscience·S CombesT Gidenne
Aug 27, 2013·Nature Biotechnology·Morgan G I LangilleCurtis Huttenhower
Nov 28, 2013·GigaScience·Yoshiki Vázquez-BaezaRob Knight
Jul 26, 2014·Bioinformatics·Donovan H ParksRobert G Beiko
Nov 25, 2014·Cell·Julia K GoodrichRuth E Ley
Apr 16, 2015·PloS One·Christine DominianniJiyoung Ahn
Aug 1, 2015·PloS One·Stéphanie C Schai-BraunKlaus Hackländer
Aug 5, 2015·Acta Veterinaria Scandinavica·Annika PosautzAnna Kübber-Heiss
May 20, 2016·International Journal of Genomics·Simon BahrndorffJeppe Lund Nielsen
Jun 30, 2016·Gut Microbes·Elin OrgAldons J Lusis

❮ Previous
Next ❯

Methods Mentioned

BETA
Assay
PCR

Software Mentioned

PERMANOVA
STAMP
lsmeans
PICRUSt
QPCR
package
Stratagene MxPro
vegan
nlme
Permutest

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.