Habitual emotion regulation strategies and depressive symptoms in healthy subjects predict fMRI brain activation patterns related to major depression

Psychiatry Research
Birgit AblerHenrik Kessler

Abstract

The response-focused emotion regulation style 'Expressive suppression' has been associated with symptoms of lower psychological well-being and increased function magnetic resonance imaging (fMRI) activation of the sublenticular extended amygdala (SLEA) in patients with major depression. Extending prior studies on active emotion regulation, we were interested in effects of habitual emotion regulation on neurobiology. Thirty subjects with either relatively high or low suppression scores as assessed with the Emotion Regulation Questionnaire without symptoms of clinical depression participated in the study. They were instructed to expect and then perceive emotionally unpleasant, pleasant or neutral stimuli selected from the International Affective Picture System that were announced by a congruent cue during fMRI. In the subjects with high suppression scores, decreased activation of the orbital medial prefrontal cortex (oMFC) when expecting negative pictures and increased activation of the SLEA upon presentation of neutral stimuli were found. Subclinical depression ratings independently of suppression scores in the healthy subjects were positively correlated with brain activation in the SLEA when expecting negative pictures. SLEA hy...Continue Reading

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Citations

Jun 1, 2012·Depression Research and Treatment·Christian PietrekBrigitte Rockstroh
Oct 27, 2010·NeuroImage·Veronika I MüllerSimon B Eickhoff
Jul 15, 2015·International Journal of Group Psychotherapy·Jacqueline L Kinley, Sandra M Reyno
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Jun 10, 2014·Frontiers in Psychology·Gabriele BuruckDenise Dörfel
May 23, 2014·Frontiers in Behavioral Neuroscience·Rosalux FalquezSven Barnow
Aug 29, 2014·PloS One·Deborah HerktBirgit Abler
Aug 21, 2016·Psychiatry Research·Helena DruryShelley Channon
Aug 1, 2019·The Journal of Head Trauma Rehabilitation·Angelle M SanderNoelle E Carlozzi
Nov 23, 2017·Frontiers in Human Neuroscience·Xiaoxia WangZhengzhi Feng
Feb 16, 2021·NeuroImage. Clinical·Emily S NicholsElizabeth A Osuch
Jun 16, 2021·Cognitive, Affective & Behavioral Neuroscience·Leah A GrandePilyoung Kim
Jul 14, 2021·NeuroImage·Julian GaviriaPatrik Vuilleumier

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