PMID: 7428308Jan 1, 1980

Haematological indices in normal negro children: a Jamaican cohort from birth to five years

Clinical and Laboratory Haematology
G SerjeantS Vaidya

Abstract

Haematological indices, including total haemoglobin, mean cell haemoglobin concentration, red cell count, mean cell volume, mean cell haemoglobin, reticulocytes, and serum iron values, in a cohort of 243 randomly selected Negro children with normal haemoglobin genotype, followed from birth to 5 years, are reported. Total haemoglobin fell rapidly from high levels at birth to a plateau at 2-6 months; a secondary fall occurred after 6 months and a gradual increase after 18 months. The red cell count also fell rapidly, but increased after 2 months to a plateau and then slowly declined from age 1-5. Mean cell volume and mean cell haemoglobin fell continuously from birth to the lowest values at 15 months and then progressively increased to the age of 5 years. Serum iron levels were low at one year of age (mean 9.7 mumol/l) increasing slowly by age 4 and sharply by age 5. Mean cell haemoglobin concentration fell gradually to 1-1 1/2 years and then increased progressively to age 5. Values for Hb, MCHC, MCV, and MCH were consistently and often significantly lower in males before the age of 2 years, compatible with greater depletion of iron stores. Serum iron values were generally lower in males but there was no sex difference at one yea...Continue Reading

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Citations

Jan 1, 1984·Transactions of the Royal Society of Tropical Medicine and Hygiene·S AbdallaD J Weatherall
Oct 31, 2002·British Journal of Haematology·Andrea ClareG Serjeant
Aug 30, 2008·Annals of Tropical Paediatrics·A-W M Al-SaqladiB J Brabin
Aug 8, 2009·European Journal of Haematology·Javier RomeoAVENA group
Apr 21, 2007·Tropical Medicine & International Health : TM & IH·P F van RheenenB J Brabin
Jan 5, 2011·Tropical Medicine & International Health : TM & IH·Alexander HumbergBertrand Lell
Feb 1, 1994·Clinical Pediatrics·T B Newman, M J Easterling
Jun 5, 2018·Journal of Clinical Laboratory Analysis·Nsoh Godwin AnabireGideon Kofi Helegbe
Oct 30, 2019·European Journal of Pediatrics·Vera SeidelCornelia Feiterna-Sperling
Nov 1, 2010·Experimental and Therapeutic Medicine·Ulrich Mahlknecht, Simone Kaiser
Jan 1, 1988·Clinical and Laboratory Haematology·S Abdalla, S N Wickramasinghe
Apr 1, 1987·American Journal of Hematology·J D ReedE P Orringer
Jul 1, 1982·Scandinavian Journal of Haematology·S N WickramasingheD J Weatherall
Jan 1, 1982·Hemoglobin·B SerjeantW F Moo-Penn
Jan 1, 1982·Hemoglobin·L Rabb, G Serjeant

Related Concepts

Anemia, Sickle Cell
Blood
Red Blood Cell Count Measurement
Mean Corpuscular Hemoglobin Concentration Determination
Hematocrit Procedure
Eryhem
Iron
Reticulocytes
African Continental Ancestry Group

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