PMID: 8449576Jan 1, 1993Paper

Haematological manifestations of childhood brucellosis

Infection
Y A al-Eissa, M N al-Nasser

Abstract

Very few data on the frequency and diversity of haematological abnormalities occurring in brucellosis in children have been reported. In the present study 110 children (56 boys and 54 girls; age range, 2 months to 14 years) with proven brucellosis were investigated to determine the haematological changes during the active course of this infection. Anaemia was detected in 48 (44%) patients, of whom four had evidence of haemolysis. Leukopenia occurred in 33% of the cases, with neutropenia and/or lymphopenia being the most striking features encountered. Thrombocytopenia was found in six (5%) patients and pancytopenia in 15 (14%) patients, of whom one developed disseminated intravascular coagulation. Clinically detectable bleeding occurred in five (4.5%) patients whose platelet counts were significantly low. Hypersplenism, haemophagocytosis and granulomatous lesions of the bone marrow appear to play a fundamental role in producing these abnormalities of the peripheral blood. Brucellosis may be considered in patients whose blood picture reveals haemolytic anaemia, leukopenia, thrombocytopenia or pancytopenia, particularly when the disease is epidemiologically suspected.

References

Jan 1, 1991·Scandinavian Journal of Infectious Diseases·Y al-EissaA al-Mazyad
Nov 1, 1990·Annals of the Rheumatic Diseases·Y A al-EissaN M al-Jishi
Nov 1, 1990·Reviews of Infectious Diseases·W H Hall
Feb 1, 1990·The Pediatric Infectious Disease Journal·Y A al-EissaF A al-Zamil
Feb 1, 1986·European Journal of Cancer & Clinical Oncology·E M IbrahimG H Abssod
Jan 1, 1989·Social Science & Medicine·F W Kiel, M Y Khan
Apr 1, 1986·Scandinavian Journal of Haematology·M H Aysha, M A Shayib
Oct 1, 1986·Clinical Pediatrics·D C Sharda, M Lubani
Jan 1, 1985·Acta Haematologica·M A BabikerE F Ashong
Jan 1, 1986·The Journal of Infectious Diseases·E GotuzzoL Llosa
Aug 1, 1968·Annals of Internal Medicine·E C LynchC P Alfrey
Sep 1, 1983·Reviews of Infectious Diseases·E J Young
Sep 1, 1984·The Journal of Infectious Diseases·E CrosbyE Gotuzzo
Aug 1, 1983·Tropical Animal Health and Production·A I RadwanA A Al-Mukayel
Mar 1, 1983·The Journal of Infectious Diseases·S Martin-MorenoC Bascones-Casas
Feb 1, 1980·European Journal of Obstetrics, Gynecology, and Reproductive Biology·P SchreyerD Sompolinsky
Dec 1, 1962·Archives of Disease in Childhood·P W BOTHWELL
Jan 1, 1946·The Journal of Infectious Diseases·M RUIZ CASTANEDA, I G GUERRERO

❮ Previous
Next ❯

Citations

Sep 6, 2007·Indian Journal of Pediatrics·Ali BayImdat Dilek
Mar 2, 2012·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Behice KurtaranYusuf Sirin
May 12, 2010·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Erol ErduranMehmet Mutlu
Apr 25, 2001·Clinical and Laboratory Haematology·A SevincH Soylu
Aug 27, 2005·Proceedings of the National Academy of Sciences of the United States of America·Céline PujolJames B Bliska
Nov 25, 2005·Proceedings of the National Academy of Sciences of the United States of America·Wyndham W LathemWilliam E Goldman
Jan 18, 2006·Proceedings of the National Academy of Sciences of the United States of America·Luca SantiHugh S Mason
Aug 2, 2000·Proceedings of the National Academy of Sciences of the United States of America·G R Cornelis
Dec 8, 1998·The Journal of Experimental Medicine·D M MonackS Falkow
Jan 25, 2003·Journal of Pediatric Hematology/oncology·Yildiz YildirmakNimet Kayaalp
Feb 12, 2010·Journal of Pediatric Hematology/oncology·Elvan Caglar CitakDilek Arman
Dec 1, 1993·European Journal of Clinical Investigation·C FerriA L Zignego
Sep 1, 1995·The Journal of Eukaryotic Microbiology·T E NashM R Mowatt
Mar 19, 2013·Mediterranean Journal of Hematology and Infectious Diseases·Mohamed A El-KoumiSalha H Al-Zahrani
Oct 17, 2014·Qatar Medical Journal·Ali Ibrahim RahilMohamed Yahya Mohamed
Jan 1, 1996·European Journal of Pediatrics·E GalanakisP D Lapatsanis
Aug 28, 2002·Scandinavian Journal of Infectious Diseases·Antigoni TsirkaStavroula Chaloulou
Nov 17, 2015·Infectious Diseases·Bircan KayaaslanHurrem Bodur
Aug 6, 2014·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Tamer YoldasTulin Revide Sayli
May 20, 2015·Pediatrics International : Official Journal of the Japan Pediatric Society·Adalet AypakYasemin Bayram
Nov 9, 2007·International Journal of Laboratory Hematology·M YilmazB Yilmaz
Apr 18, 2009·Pediatrics International : Official Journal of the Japan Pediatric Society·Gonul TanirNilden Tuygun
Sep 15, 2015·Vector Borne and Zoonotic Diseases·Arzu KarliDavut Albayrak
Dec 4, 2014·Journal of Infection and Public Health·Ozge MetinGonul Tanir
Dec 14, 2012·PLoS Neglected Tropical Diseases·Anna S DeanJakob Zinsstag
Jun 15, 2016·Journal of Pediatric Hematology/oncology·Kamuran KaramanAhmet F Oner
Sep 11, 2010·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Sinan AkbayramAhmet Faik Oner
Sep 9, 2010·The Annals of Pharmacotherapy·Lambros K BourantasKonstantinos L Bourantas
Feb 6, 2007·Annals of Saudi Medicine·Y A Al-Eissa
Jan 28, 2017·Case Reports in Infectious Diseases·Alexandros MakisNikolaos Chaliasos
Sep 1, 1995·Annals of Tropical Paediatrics·B Benjamin
Dec 5, 2012·Internal Medicine·Sirvan Elmas DalOzlem Akdogan

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brucellosis (ASM)

Brucellosis is a bacterial infection caused by members of the genus brucella and remains one of the world's major zoonotic diseases. Discover the latest research on Brucellosis here.

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Brucellosis

Brucellosis is a bacterial infection caused by members of the genus brucella and remains one of the world's major zoonotic diseases. Discover the latest research on Brucellosis here.