Haemodialysis for paediatric acute kidney injury in a low resource setting: experience from a tertiary hospital in South West Nigeria

Clinical Kidney Journal
Adanze O AsinobiMichael A Alao

Abstract

Acute kidney injury (AKI) is an important cause of preventable mortality among children. Management of AKI may require renal replacement therapy (RRT) but access to RRT for children in low resource settings is limited. Our study explored the role of haemodialysis in the management of children with AKI in a low resource setting in terms of aetiology and outcomes. A review of patients managed in the Paediatric Nephrology Unit, University College Hospital Ibadan, South-West Nigeria, who underwent haemodialysis for AKI from January 2006 to December 2014. Sixty-eight patients (55.9% males), aged 3-16 (mean ± standard deviation, 9.0 ± 3.4) years were studied. The causes of AKI were sepsis (22.1%), malaria (17.6%) and glomerulonephritis (17.6%), intravascular haemolysis-cause unknown (16.2%), G6PDH deficiency (7.4%), malignancy (8.8%) and haemoglobinopathy (5.9%). The number of sessions of haemodialysis ranged from 1 to 10 (mode = 2 sessions) over a period of 1-55 days. Mortality was 27.9% (n = 19) and was related to the aetiology of AKI (P = 0.000): no deaths among patients with intravascular haemolysis or malaria, six deaths among patients with sepsis (40%), six (50%) among the patients with glomerulonephritis, while all the patient...Continue Reading

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Citations

Dec 6, 2017·Current Opinion in Infectious Diseases·Katherine PlewesArjen M Dondorp
Sep 28, 2018·Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis·Rhys D R EvansUlla Hemmila
Nov 12, 2020·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Adewale E AdetunjiGeorge O Akpede

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