Haemodialysis is associated with changes in cutaneous microcirculation in diabetes mellitus

Diabetic Medicine : a Journal of the British Diabetic Association
S BeckertStephan Coerper

Abstract

To examine the cutaneous microcirculation on the dorsum of the foot before, during and after haemodialysis in diabetic and non-diabetic patients. Fourteen age-matched patients (seven diabetic, seven non-diabetic) without active foot ulceration were studied. Cutaneous microcirculation was assessed using a micro-lightguide spectrophotometer to measure venous oxygen saturation and relative blood flow determined at two tissue depths: 2 and 6 mm. Cumulative relative changes of each parameter during haemodialysis were calculated as area under the curve. Differences between and within the groups were calculated by Mann-Whitney U-test and anova following post hoc testing, respectively. At baseline, relative blood flow at 6 mm tissue depth was significantly greater in diabetic patients (P = 0.048). Thirty minutes after the end of dialysis, relative blood flow at 2 and 6 mm tissue depth was significantly higher in non-diabetic patients (P = 0.048 and P = 0.001). Mean cumulative relative changes in venous oxygen saturation and relative blood flow at 2 mm as well as 6 mm tissue depth were positive for non-diabetic subjects and negative for diabetic patients. Haemodialysis is associated with changes in cutaneous microcirculation, which diff...Continue Reading

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References

Oct 20, 1977·The New England Journal of Medicine·N M AurigemmaE G Lowrie
Jan 1, 1984·American Journal of Nephrology·S Garella, B S Chang
Nov 1, 1996·Clinical Science·P M NettenJ A Lutterman
Jan 28, 1998·American Journal of Surgery·T IkedaJ West
Jul 3, 1998·Diabetes Research and Clinical Practice·M LunettaL Sangiorgio
Jul 22, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Michael KochBernd Grabensee
Sep 10, 2005·Clinical Neurology and Neurosurgery·Ali MoghtaderiHomayra Rashidi
Feb 2, 2006·Diabetes Research and Clinical Practice·Vilma Urbancic-RovanAndreja Kocijancic
May 17, 2006·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Robert J HinchliffeFran Game
Aug 1, 2006·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Frances L GameWilliam J Jeffcoate

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Citations

Jun 10, 2010·Current Diabetes Reports·Agbor NdipAndrew J M Boulton
Feb 6, 2014·The Pan African Medical Journal·Nawal BenabdellahIntissar Haddiya
Aug 16, 2012·International Wound Journal·Nia J JonesStephen G Riley
May 7, 2015·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Michelle R KaminskiKarl B Landorf
Jun 26, 2012·Journal of Vascular Surgery·Lise Pyndt Jørgensen, Torben V Schroeder
Sep 4, 2012·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Dan M J MilsteinJérôme A H Lindeboom
Jul 28, 2016·World Journal of Nephrology·Meltem GursuRumeyza Kazancioglu
Dec 6, 2018·Seminars in Dialysis·Clare MacEwenChristopher Pugh
Dec 15, 2020·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Eun Young SeongTara I Chang
Jun 11, 2020·Case Reports in Nephrology and Dialysis·Jinichi MoriTetsuya Tanimoto

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