PMID: 9442370Jan 27, 1998Paper

Haemodynamic actions of insulin

Current Opinion in Nephrology and Hypertension
C J TackT Thien

Abstract

Several lines of evidence indicate a significant association between insulin and cardiovascular disease. This association might be explained by direct (cardio) vascular effects of insulin. Two hemodynamic actions of insulin are discussed in this review; it induces direct vasodilation in skeletal muscle and stimulation of the sympathetic nervous system. These closely linked effects normally offset each other. Although more insight has been obtained into responses in insulin-resistant individuals and possible mechanisms, direct evidence to support a causative role for insulin is not yet available.

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Citations

Nov 6, 2008·Acta Physiologica·M Rupnik
Mar 6, 2013·Canadian Journal of Physiology and Pharmacology·Kawshik K ChowdhuryW Wayne Lautt
Apr 24, 2007·Journal of Korean Medical Science·Chul-Woo JungKook-Hyun Lee
Sep 11, 2010·Journal of Applied Physiology·Zhi Ming, W Wayne Lautt
Jan 15, 2002·American Journal of Physiology. Endocrinology and Metabolism·Mary Courtney MooreAlan D Cherrington
Sep 2, 1999·Journal of Cardiovascular Pharmacology·E J Abbink-ZandbergenP Smits
Dec 30, 1998·Journal of Hypertension·T C Fang, W C Huang

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