Haemodynamic analysis for recanalisation of intracranial aneurysms after endovascular treatment: an observational registry study in China

BMJ Open
Jian LiuXinjian Yang

Abstract

Recanalisation of intracranial aneurysms following endovascular treatment is a major issue. Many factors, including aneurysm morphology, the method of treatment, and haemodynamics, are considered to be associated with recanalisation. However, the underlying haemodynamic mechanisms are not completely understood. This is a prospective, observational, registry study for patients with intracranial aneurysms who are treated endovascularly. It will enrol 200 eligible patients. Data on morphological, haemodynamic, and treatment factors will be collected prospectively. The advanced virtual stenting technique and porous media method will be used in haemodynamic simulations. The clinical and angiographic outcomes at 6 months will be measured and analysed. This observational study will determine the haemodynamic factors that affect the recanalisation of aneurysms. Both the study protocol and written informed consent were reviewed and approved by the Institutional Review Board of Beijing Tiantan Hospital (KY2016-023-01). The results of study will be disseminated in professional printed media. NCT02812108; Pre-results.

Methods Mentioned

BETA
dissecting

Clinical Trials Mentioned

NCT02812108

Software Mentioned

SPSS
HARET
Geomagic Studio
ANSYS CFX
ICEM CFD
ANSYS CFD -

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