PMID: 9426094Jan 13, 1998Paper

Haemodynamic and endocrinological effects of noninvasive mechanical ventilation in respiratory failure

The European Respiratory Journal
J B ThorensJ C Chevrolet

Abstract

The aim of this study was to investigate the haemodynamic and endocrinological effects of noninvasive positive pressure ventilation (NIPPV). Eleven patients with oedema and recent hypercapnic and hypoxaemic worsening of a chronic respiratory insufficiency were included. Echocardiography, cardiac radionuclide assessment, blood catecholamines, salt and water handling hormones were measured at admission and discharge (long study (LS)). To discriminate between the action of NIPPV and other treatments, measurements were performed on the fourth day, for 4 h without NIPPV and 4 h with NIPPV (short study (SS)). NIPPV entailed a correction of P(a,CO2) and an increase of P(a,O2) in LS and SS. Oedema disappeared. Body weight decreased (from 85+/-42 to 81+/-40 kg) during LS. Systolic and mean pulmonary arterial pressure decreased in LS and SS. Right ventricular ejection fraction increased in LS. Left ventricular ejection fraction did not change. Cardiac index was normal on admission and then decreased. Natriuretic peptides and catecholamines were increased on admission, whereas plasma renin activity, aldosterone and vasopressin were normal. We suggest that in these patients, oedema can occur independently of renin-angiotensin-aldosterone-v...Continue Reading

Citations

Dec 15, 2005·Heart, Lung & Circulation·David R SullivanRichmond Jeremy
May 7, 2002·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·R L SummersJ C Kolb
Feb 17, 2001·American Journal of Respiratory and Critical Care Medicine·S Mehta, N S Hill
Jul 13, 2013·International Journal of Chronic Obstructive Pulmonary Disease·Javier de Miguel DíezRodrigo Jiménez García
Feb 7, 2014·Herz·S WalterspacherM Dreher
Jul 15, 2009·Archivos de bronconeumología·Felipe Villar AlvarezJavier de Miguel Díez
Jun 14, 2015·Australian Critical Care : Official Journal of the Confederation of Australian Critical Care Nurses·Guniz M KoksalAntonio M Esquinas
Dec 29, 2009·Medicina clínica·Javier Muñoz BonoJuan Luis Galeas López
Aug 2, 2007·American Journal of Physical Medicine & Rehabilitation·Brian VilaJohn Bach
Mar 15, 2006·Current Opinion in Anaesthesiology·Reto Stocker, Peter Biro

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