PMID: 6980657Aug 1, 1982Paper

Haemodynamic effects of midazolam and thiopentone during induction of anaesthesia for coronary artery surgery

British Journal of Anaesthesia
D Al-KhudhairiS Powrie

Abstract

The cardiovascular effects of thiopentone 3 mg kg-1 and midazolam 0.3 mg kg-1 were observed during induction of anaesthesia in 16 premedicated patients about to undergo myocardial revascularization. There were no significant changes in either group in cardiac output or central venous pressure. The heart rate in both groups showed an increase at 3 min and thereafter returned to control values. After 3 min, there was a significant decrease in both arterial pressure and peripheral resistance by 12% and 15% (mean values) respectively from control values in the group receiving midazolam, whereas after thiopentone the peripheral resistance increased by approximately 13% and was not affected by a further dose of thiopentone 1 mg kg-1.

Citations

Mar 3, 1999·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·T MurphyR I Hall
Jan 1, 1997·Archives of Disease in Childhood·L ShekerdemianA Redington
Jan 1, 1991·Intensive Care Medicine·R Amrein, W Hetzel
May 1, 1989·Gastrointestinal Endoscopy·R H HartkeN C Abbey
Aug 13, 2010·Acta Anaesthesiologica Scandinavica·A G JensenUNKNOWN Clinical Practice Committee of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine
Oct 1, 1993·Journal of Cardiothoracic and Vascular Anesthesia·M Newman, J G Reves
Oct 7, 2006·Journal of Cardiothoracic and Vascular Anesthesia·Bryan HarrisStuart Jamieson
Jan 1, 1987·Annales Françaises D'anesthèsie Et De Rèanimation·J Kienlen, J du Cailar
Oct 1, 1986·Acta Anaesthesiologica Scandinavica·A L Pauca, R C Roy
Dec 10, 1999·Anesthesia and Analgesia·G D WilliamsJ P Morray
Jan 1, 1984·Anaesthesia·D R DerbyshireG Smith
May 1, 1986·Anaesthesia and Intensive Care·A A ArtruB Wright

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.