Haemodynamic response to exercise in healthy young and elderly subjects

European Journal of Applied Physiology and Occupational Physiology
H J BogaardP M de Vries

Abstract

Whereas with advancing age, peak heart rate (HR) and cardiac index (CI) are clearly reduced, peak stroke index (SI) may decrease, remain constant or even increase. The aim of this study was to describe the patterns of HR, SI, CI, arteriovenous difference in oxygen concentration (Ca-vO2), mean arterial pressure (MAP), systemic vascular resistance index (SVRI), stroke work index (SWI) and mean systolic ejection rate index (MSERI) in two age groups (A: 20-30 years, n = 20; B: 50-60 years n = 20). After determination of pulmonary function, an incremental bicycle exercise test was performed, with standard, gas-exchange measurements and SI assessment using electrical impedance cardiography. The following age-related changes were found: similar submaximal HR response to exercise in both groups and a higher peak HR in A than in B[185 (SD 9) vs 167 (SD 14) beats.min-1, P < 0.0005]; increase in SI with exercise up to 60-90 W and subsequent stabilization in both groups. As SI decreased towards the end of exercise in B, a higher peak SI was found in A [57.5 (SD 14.0) vs 43.6 (SD 7.7) ml.m-2, P < 0.0005]; similar submaximal CI response-to exercise, higher peak CI in A [10.6 (SD 2.5) vs 7.2 (SD 1.3) 1.min-1.m-2, P < 0.0005]; no differences i...Continue Reading

Citations

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