Haemonchotolerance in West African Dwarf goats: contribution to sustainable, anthelmintics-free helminth control in traditionally managed Nigerian dwarf goats

Parasite : Journal De La Société Française De Parasitologie
S N ChiejinaB B Fakae

Abstract

West African Dwarf (WAD) goats are extremely important in the rural village economy of West Africa, but still little is known about their biology, ecology and capacity to cope with gastrointestinal nematode (GIN) infections. Here, we summarise the history of this breed and explain its economic importance in rural West Africa. We review recent work showing that Nigerian WAD goats are highly trypanotolerant and resist infections with Haemonchus contortus more effectively than other breeds of domestic goat (haemonchotolerance). We believe that haemonchotolerance is largely responsible for the generally low level GIN infections and absence of clinical haemonchosis in WADs under field conditions, and has contributed to the relatively successful and sustainable, anthelmintics-free, small-scale system of goat husbandry in Nigeria's humid zone, and is immunologically based and genetically controlled. If haemonchotolerance can be shown to be genetically controlled, it should be possible to exploit the underlying genes to improve GIN resistance among productive fibre and milk producing breeds of goats, most of which are highly susceptible to nematode infections. Genetic resistance to GIN and trypanosome infections would obviate the need ...Continue Reading

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Citations

May 29, 2015·Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis·Guangjie Luo, Jicheng Liao
Jan 15, 2020·Journal of Veterinary Research·Sergio Aurelio ZanzaniMaria Teresa Manfredi
Aug 21, 2021·Frontiers in Genetics·Bruno SerranitoAnne Da Silva

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