Haemophilus influenzae infections in Fresno County, California: a prospective study of the effects of age, race, and contact with a case on incidence of disease

The Journal of Infectious Diseases
D M Granoff, M Basden

Abstract

A prospective, population-based study of the incidence of infections with Haemophilus influenzae in Fresno County, California, was conducted. The average annual incidence or meningitis was 5.18 cases per 100,000 population, and of other invasive infections, 3.48 cases per 100,000. Incidence rates were highest in infants, but 13% of infections and five of seven deaths were in adults, primarily in elderly individuals with compromised defenses. Black children four years of age and younger were more susceptible to meningitis due to H. influenzae than were white children (P less than 0.001). In contrast, the increased incidence of haemophilus disease in Hispanic children was primarily a result of invasive infections other than meningitis (P less than 0.03). The secondary attack rate in household contacts less than two years of age was one in 24 during the first 30 days, one in 23 between 31 and 60 days, and 0.25 in 22 per month between three and six months. Age and racial factors may affect susceptibility to different forms of invasive disease due to H. influenzae, and young contacts of a patient are at increased risk of developing illness.

Citations

Aug 1, 1994·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·F DeulofeuA Calderón
Sep 2, 1999·Infectious Disease Clinics of North America·R Gold
Aug 1, 1997·The Pediatric Infectious Disease Journal·H Peltola
Dec 1, 1987·Australian Paediatric Journal·G L Gilbert
Nov 1, 1981·Archives of Disease in Childhood·H D Wilson
May 1, 1990·Archives of Disease in Childhood·B TrollforsK Strangert
Mar 9, 1991·BMJ : British Medical Journal·K A CartwrightD Hull
Jan 13, 2011·The British Journal of Radiology·F OkadaH Mori
Feb 1, 1985·The American Journal of the Medical Sciences·T E Liston
Jan 21, 2009·The Journal of Infection·Shamez LadhaniMary E Ramsay
Feb 3, 2005·Biological Reviews of the Cambridge Philosophical Society·Bruno A Walther, Paul W Ewald
May 19, 2010·International Journal of Immunogenetics·M O JoannesT Marianne-Pepin
Mar 1, 1986·Current Problems in Pediatrics·F J CrossonA S Yeager
Aug 1, 1987·The Journal of Pediatrics·M I Marks, W L Dorchester
Sep 1, 1985·The Journal of Pediatrics·D M Granoff, K L Cates
May 1, 1987·The Journal of Infection·J EskolaP H Mäkelä
Jun 29, 2013·Human Vaccines & Immunotherapeutics·Dan M Granoff
Aug 1, 1994·Journal of Paediatrics and Child Health·T Lipson
Jan 1, 1981·Critical Reviews in Clinical Laboratory Sciences·H D Riley
Jan 1, 1981·Critical Reviews in Clinical Laboratory Sciences·H D Riley
Dec 1, 1991·The Journal of Pediatrics·D M AmbrosinoG M Carlone
Oct 1, 1982·Clinical Pediatrics·S D HandlerJ J Downes
May 1, 1984·Clinical Pediatrics·H Peltola, M Virtanen
Jun 1, 1982·Clinical Pediatrics·S J Lerman

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy & Infectious Diseases

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Allergy & Infectious Diseases (ASM)

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.

Bacterial Meningitis

Bacterial meningitis continues to be an important cause of mortality and morbidity throughout the world. Here is the latest research.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Bacterial Meningitis (ASM)

Bacterial meningitis continues to be an important cause of mortality and morbidity throughout the world. Here is the latest research.