Hairy cell leukemia involving an inguinal hernial sac

Acta Haematologica
M J MelaragnoB A Bouroncle

Abstract

A 37-year-old man with hairy cell leukemia was found incidentally to have a right inguinal hernia. Microscopic examination of the resected herniorrhaphy specimen disclosed dense transmural infiltration by hairy cells. Electron-microscopic and immunoperoxidase studies confirmed the presence of surface cytoplasmic projections and B cell phenotype, respectively, of the infiltrating cells. This case is, to our knowledge, the first reported instance of hairy cell leukemia involving a hernial sac and demonstrates the capacity of hairy cells to infiltrate unexpected soft-tissue sites.

Citations

Apr 3, 2003·Best Practice & Research. Clinical Haematology·Kelly J Bethel, Robert W Sharpe
Jan 21, 2003·Leukemia & Lymphoma·A LalLoann Peterson
Sep 23, 2006·Hematology/oncology Clinics of North America·Robert W Sharpe, Kelly J Bethel
Mar 19, 2015·Clinical Nuclear Medicine·Glenna GibsonPaul Thomas

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