PMID: 8942Jan 1, 1976

Halothane anaesthesia in caesarean section

Acta Anaesthesiologica Scandinavica
L KangasM Mansikka

Abstract

The safety and efficacy of halothane anaesthesia were investigated in 97 caesarean sections using 0.4-0.6% halothane added to a mixture of 61 N2O/3-4 1 O2. The administration of halothane was initiated before intubation and terminated immediately prior to delivery. Only one patient reported memories from the operation. The mean Apgar score 1 min after delivery (8.5) was significantly better than that (8.2) in 100 caesarean sections in which a mixture of 71 N2O/3 1 O2 was used. In 17 caesarean sections, the halothane concentrations were examined after 0.9% halothane had been given for exactly 1 min after intubation. It was found that halothane reached and passed the placenta after only 1 min. The levels in the maternal artery and umbilical vein were comparable. The levels in the maternal artery, maternal vein and umbilical vein were markedly higher than in the umbilical artery, which indicated an accumulation of halothane in the foetal tissues. However, due to the vigour of the newborn, halothane concentrations 10 min after birth were very low. The half-life of halothane in the maternal circulation was approximately 1 min with the described method of administration. Blood gas determinations, which were made in seven newborns, pr...Continue Reading

References

Jul 1, 1973·Anesthesia and Analgesia·G F MarxS Halevy
Oct 1, 1972·British Journal of Anaesthesia·M M Atallah, I C Geddes
Sep 1, 1972·Anesthesia and Analgesia·M W Galbert, A E Gardner
Jun 1, 1972·British Journal of Anaesthesia·I C GeddesL Mark
Feb 1, 1970·British Journal of Anaesthesia·R DouglasD G Wood
Oct 1, 1968·Anaesthesia·M J RorkeH J Du Toit
Feb 1, 1969·British Medical Journal·J Wilson, D J Turner
Jan 1, 1969·The Journal of Obstetrics and Gynaecology of the British Commonwealth·E S MunsonD Caton
Jul 1, 1959·British Journal of Anaesthesia·W A DUNCAN, J RAVENTOS
Jun 1, 1962·British Journal of Anaesthesia·J S CRAWFORD
Sep 1, 1963·Clinical Pharmacology and Therapeutics·F MOYA, V THORNDIKE
Oct 1, 1959·Canadian Anaesthetists' Society Journal·C A SHERIDAN, J G ROBSON

Citations

Aug 1, 1979·Acta Anaesthesiologica Scandinavica·M SaloO P Lehtonen
Feb 12, 2013·Seminars in Pediatric Surgery·Elaina E Lin, Kha M Tran
Jun 23, 2009·Seminars in Fetal & Neonatal Medicine·Kha M Tran
Oct 1, 1989·Acta Anaesthesiologica Scandinavica·T K AbboudA Afrasiabi
Apr 1, 1982·Acta Anaesthesiologica Scandinavica·J Dich-Nielsen, J Holasek
Dec 1, 1982·Acta Anaesthesiologica Scandinavica·J Kanto, U Klotz
Oct 1, 1985·Acta Anaesthesiologica Scandinavica·T K AbboudS M Shnider
May 4, 2016·Indian Journal of Anaesthesia·Madhusudan Upadya, P J Saneesh
Dec 10, 2009·Pharmacoepidemiology and Drug Safety·János GidaiAndrew E Czeizel
Jun 1, 1978·Acta Pathologica Et Microbiologica Scandinavica. Section C, Immunology·M SaloL Kangas

Related Concepts

Insufflation Anesthesia
Paracervical Block
Apgar Score
Carbon Dioxide
Postcesarean Section
Umbilical Cord Blood
Narcotan
Hydrogen-Ion Concentration
Dioxygen

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