Hand-Assisted laparoscopic donor nephrectomy PERiumbilical versus Pfannenstiel incision and return to normal physical ACTivity (HAPERPACT): study protocol for a randomized controlled trial

Trials
Yakup KuluArianeb Mehrabi

Abstract

Hand-assisted laparoscopic living donor nephrectomy (HALDN) using a periumbilical or Pfannenstiel incision was developed to improve donor outcome after a kidney transplant. The aim of this study was to investigate two methods of hand assistance and kidney removal during HALDN and their effect on the time it takes for the donor to return to normal physical activity. This study was initiated in November 2017 and is expected to last for 2 years. To be eligible for the study, donors must be more than 20 years of age and must not be receiving permanent pain therapy. Only donors with a single artery and vein in the graft are being enrolled in this trial. Donors with infections or scars in the periumbilical or hypogastric area, bleeding disorders, chronic use of immunosuppressive agents, or active infection will be excluded. Donors will be randomly allocated to either a control arm (periumbilical incision) or an intervention arm (Pfannenstiel incision). The sample size was calculated as 26 organ donors in each group. The primary endpoint is the number of days it takes the donor to return to normal physical activity (up to 4 weeks after the operation). Secondary endpoints are intraoperative outcomes, including estimated blood loss, war...Continue Reading

References

Nov 14, 1997·Annals of Surgery·J L FlowersS T Bartlett
Nov 4, 1998·Urology·J S WolfR M Merion
Feb 12, 2000·Transplantation·C R SmithM A Schnitzler
Aug 2, 2002·Transplantation·Ergun VelidedeogluJames F Markmann
Nov 11, 2006·Journal of Endourology·Vladislav BargmanWilliam Goggins
Nov 15, 2006·Clinical Transplantation·Jürgen WeitzJan Schmidt
Dec 26, 2006·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·M v FrankenbergM W Büchler
Dec 20, 2007·Plastic and Reconstructive Surgery·Adam J SingerJudd E Hollander
Oct 25, 2011·The International Journal of Behavioral Nutrition and Physical Activity·Paul H LeeSunita M Stewart
Jul 16, 2016·Revista da Escola de Enfermagem da U S P·Renata Eloah de Lucena Ferretti-RebustiniRicardo Nitrini
Nov 9, 2016·Scandinavian Journal of Urology·Majken Højrup WiborgLars Lund
May 26, 2017·Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia·Durre ShohabSaeed Akhter

❮ Previous
Next ❯

Clinical Trials Mentioned

NCT03317184

Software Mentioned

HAPERPACT
Excel®
AddPlan
SPSS

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.