"Hanging donors": are we still skeptical about the lungs?

Transplantation Proceedings
Prashant N MohiteAndré R Simon

Abstract

Suicidal hanging may cause compression of the neck blood vessels and the airway leading, to hypoxic brain damage caused by cerebral ischemia and respiratory distress. Hanging engenders global tissue hypoxia, particularly affecting the lungs as the result of pulmonary edema and barotrauma. There is scant evidence about outcomes of transplantation with the use of lungs from "hanging donors." This study evaluates the outcomes of lung transplantations (LTx) that use organs from this group. We retrospectively analyzed lung "organ offers" and LTx at our center between January 2007 and November 2013. The outcomes of LTx with lungs from donors with hanging as the cause of death ("hanging group") were compared with those with donors having other causes of death (control group), with the use of an unadjusted model as well as propensity score matching. LTx (n = 302) were performed during this period and were grouped on the basis of the cause of death in donors: the hanging group (n = 8) and the control group (n = 294). No statistically significant difference was found in the donor characteristics except for the incidence of cardiac arrest, which was significantly higher in hanging donors. Preoperative characteristics in recipients in both...Continue Reading

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Citations

Jun 28, 2018·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Patrick B TrotterJ Andrew Bradley
Nov 24, 2019·Clinical Transplantation·Julien De WolfEdouard Sage
Sep 13, 2019·Interactive Cardiovascular and Thoracic Surgery·João Santos SilvaPierre-Emmanuel Falcoz
Jan 13, 2017·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Prashant N MohiteAndré R Simon
Aug 31, 2018·Journal of the Intensive Care Society·William Jc Sutcliffe, Anton G Saayman

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