PMID: 11340492May 8, 2001Paper

Hantavirus pulmonary and cardiovascular syndrome: epidemiology, clinical presentation, laboratory diagnosis and treatment

Revista Da Sociedade Brasileira De Medicina Tropical
L T FigueiredoF B Rodrigues

Abstract

The Hantavirus pulmonary and cardiovascular syndrome (HPCVS) is an emerging disease in Brazil. In this study, eight confirmed cases of HPCVS were studied. All the patients presented fever and dyspnea as well as thrombocytopenia and hypoxemia. Tachycardia, malaise, hypotension and lung rales occurred in 75 to 87.5% of the cases. Hemoconcentration, blood cell count increased and immature neutrophils, and high levels of creatinine were observed in 75 to 87.5%. Intravenous liquid infusion, the use of drugs for increasing systemic vascular resistance and inotropism, and mechanic ventilation were used for the patients. Mechanical ventilation and volume administration should be started precociously, preferable in intensive care units employing recommended universal and respiratory precautions. Careful volume administration should be limited if signs of pulmonary edema develop. Mortality (50%) is high and probably related to the severity of the disease as well as to a delayed attending of the patients for intensive management. It is important to report hantaviruses and HPCVS to the Brazilian medical community considering that many cases could be undiagnosed.

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Citations

Feb 23, 2011·Revista Da Sociedade Brasileira De Medicina Tropical·Janduhy Pereira dos SantosMarco Túlio Antônio García-Zapata
Apr 6, 2012·Transactions of the Royal Society of Tropical Medicine and Hygiene·Mauro da Rosa ElkhouryPedro Fernando da Costa Vasconcelos
Aug 6, 2003·Emerging Infectious Diseases·Luiz T M FigueiredoRicardo L M Sousa
May 8, 2008·Cadernos de saúde pública·Maria Rita DonalisioGiselda Katz
Mar 31, 2010·Journal of Thoracic Imaging·Fabrício Guimarães GonçalvesPriscilla Ornellas Neves
Mar 8, 2014·Revista Da Sociedade Brasileira De Medicina Tropical·Maria Cristina Antunes Willemann, Stefan Vilges de Oliveira
Oct 19, 2002·Memórias do Instituto Oswaldo Cruz·Mario León Silva-VergaraAlan César Teixeira
Jul 19, 2006·Emerging Infectious Diseases·Marcelo Cordeiro dos SantosMaria Paula Gomes Mourão
Sep 14, 2010·Memórias do Instituto Oswaldo Cruz·Daniele B A MedeirosMárcio R T Nunes
Feb 3, 2007·The British Journal of Radiology·E L GasparettoE Marchiori
Oct 26, 2016·PloS One·Paula Ribeiro PristJean Paul Metzger
Jun 6, 2018·Anatomia, histologia, embryologia·Lara Carolina MarioMaria A Miglino
Oct 17, 2019·Revista Do Instituto De Medicina Tropical De São Paulo·João Paulo Vieira Dos SantosAdilha Misson Rua Micheletti
Jul 4, 2017·Radiologia brasileira·Diego de Lacerda BarbosaEdson Marchiori

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