PMID: 29769944Jun 4, 2015Paper

Hantavirus pulmonary syndrome in Canada: An overview of clinical features, diagnostics, epidemiology and prevention

Canada Communicable Disease Report = Relevé Des Maladies Transmissibles Au Canada
Michael A DrebotR Lindsay

Abstract

Hantavirus pulmonary syndrome is a disease caused by the inhalation of excreta from infected deer mice. In Canada, the majority of hantavirus pulmonary syndrome cases occur in the western provinces of British Columbia, Alberta, Saskatchewan and Manitoba and the primary cause of the illness is the Sin Nombre virus. Only one case of hantavirus pulmonary syndrome has been documented in eastern Canada (Québec); however, Sin Nombre virus-infected deer mice have been identified across the country. Although cases are rare (yearly case numbers range from zero to 13 and the total number of confirmed cases in Canada now total 109), the mortality rate among infected individuals is approximately 30%. The majority of cases occur in the spring and early summer indicating seasonally-associated risk factors for viral exposure. In 2013 and 2014, a substantial increase in the number of hantavirus pulmonary syndrome cases was identified; however the cause remains unclear. No antivirals or vaccines are currently available and treatment is supportive. Public education, rodent control and the use of personal protective measures are key to avoid infections in at-risk populations.

Citations

Aug 28, 2020·Frontiers in Bioengineering and Biotechnology·Michael Hilary D'Souza, Trushar R Patel
Dec 21, 2019·Revista Do Instituto De Medicina Tropical De São Paulo·Ana Cláudia Pereira Terças-TrettelElba Regina Sampaio de Lemos
Jul 7, 2019·Viruses·Rebecca L Brocato, Jay W Hooper
Nov 22, 2020·Emerging Infectious Diseases·Bryce M WarnerDavid Safronetz
Oct 1, 2016·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Pooja R MurthyDipak Chaudhari
May 13, 2021·Case Reports in Infectious Diseases·S RupasingheA Rajaratnam
Jul 3, 2021·Viruses·Ana Cláudia Pereira Terças-TrettelElba Regina Sampaio de Lemos

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