Harmonic distortion on the basilar membrane in the basal turn of the guinea-pig cochlea

The Journal of Physiology
N P Cooper

Abstract

1. Mechanical responses to pure-tone stimuli were recorded from the basilar membrane in the basal turn of the guinea-pig cochlea using a displacement-sensitive laser interferometer. The harmonic content of the responses was evaluated using Fourier analysis. 2. Harmonic distortion products were observed in many of the basilar membrane responses. Response components locked to twice the frequency of the stimulus (i.e. 2F0) were the largest of the distortion products. 3. The second harmonic responses showed a bimodal frequency distribution at low to moderate sound pressure levels: one peak occurred around the preparation's best or most sensitive frequency (i.e. when F0 approximately 17 kHz), and another occurred around one-half of the best frequency (when F0 approximately 8.5 kHz). 4. The absolute levels of most distortion products increased progressively with increasing stimulus strength. When expressed with respect to the levels of the fundamental responses, however, the distortion levels usually decreased with increasing stimulus strength. 5. The levels of the distortion decreased (in both absolute and relative terms) with deterioration in the physiological condition of the cochlea. 6. Maximum second harmonic distortion levels a...Continue Reading

References

Jun 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·A J Hudspeth, D P Corey
Jan 1, 1979·The Journal of the Acoustical Society of America·J R JohnstoneG K Yates
Nov 1, 1978·The Journal of Physiology·I J Russell, P M Sellick
Aug 22, 1992·Proceedings. Biological Sciences·C J KrosG P Richardson
Jan 1, 1989·Acta Oto-laryngologica. Supplementum·S M KhannaA Flock
Oct 1, 1989·Hearing Research·R B PatuzziB M Johnstone
Nov 1, 1989·The Journal of the Acoustical Society of America·P Dallos, M A Cheatham
Oct 1, 1988·Physiological Reviews·R Patuzzi, D Robertson
Feb 1, 1987·The Journal of Physiology·A R Cody, I J Russell
Jan 1, 1986·Hearing Research·N Y KiangJ J Guinan
Jul 1, 1986·The Journal of the Acoustical Society of America·E Zwicker
Apr 1, 1971·The Journal of the Acoustical Society of America·W S Rhode
Mar 1, 1967·The Journal of the Acoustical Society of America·J L Goldstein
Jan 1, 1983·Hearing Research·H Davis
Jul 1, 1982·The Journal of the Acoustical Society of America·P M SellickB M Johnstone
Nov 1, 1993·Biophysical Journal·J Santos-Sacchi
Jun 1, 1995·Hearing Research·C D Geisler, C Sang
May 1, 1996·The Journal of the Acoustical Society of America·N P Cooper
Apr 1, 1996·The Journal of the Acoustical Society of America·R Nobili, F Mammano
Mar 1, 1996·The Journal of the Acoustical Society of America·A L Nuttall, D F Dolan
Aug 1, 1997·The Journal of the Acoustical Society of America·M A Cheatham, P Dallos

❮ Previous
Next ❯

Citations

Mar 1, 2005·Journal of the Association for Research in Otolaryngology : JARO·Colleen G Le PrellSanford C Bledsoe
Mar 29, 2006·Journal of the Association for Research in Otolaryngology : JARO·Shawn S Goodman, Douglas H Keefe
Jun 6, 2009·Journal of the Association for Research in Otolaryngology : JARO·Alberto Recio-SpinosoMario A Ruggero
Oct 3, 2009·Journal of the Association for Research in Otolaryngology : JARO·Wei Zhao, Sumitrajit Dhar
Oct 20, 2010·Journal of the Association for Research in Otolaryngology : JARO·Mary Ann CheathamPeter Dallos
Jan 27, 2011·Journal of the Association for Research in Otolaryngology : JARO·Skyler G JenningsElizabeth A Strickland
Mar 3, 2011·Journal of the Association for Research in Otolaryngology : JARO·Diego ElguedaLuis Robles
Jan 31, 2012·Journal of the Association for Research in Otolaryngology : JARO·Ananthakrishna ChintanpalliElizabeth A Strickland
Mar 3, 2009·Molecular Neurobiology·George Zanazzi, Gary Matthews
Oct 18, 2000·Hearing Research·S M Khanna, L F Hao
Sep 24, 1999·Hearing Research·S M Khanna, L F Hao
Jan 12, 2005·Nature Neuroscience·Dylan K Chan, A J Hudspeth
Mar 15, 2001·Proceedings of the National Academy of Sciences of the United States of America·A B ElgoyhenJ Boulter
Dec 14, 2007·Proceedings of the National Academy of Sciences of the United States of America·Douglas E VetterJim Boulter
Feb 6, 2010·Proceedings of the National Academy of Sciences of the United States of America·Richard D RabbittStephen M Highstein
Dec 4, 2002·Proceedings of the National Academy of Sciences of the United States of America·Tianying Ren
Mar 18, 1997·Proceedings of the National Academy of Sciences of the United States of America·I J Russell, K E Nilsen
Mar 31, 1999·Proceedings of the National Academy of Sciences of the United States of America·P J Kolston
Oct 26, 2000·Proceedings of the National Academy of Sciences of the United States of America·K E Nilsen, I J Russell
Jan 27, 2006·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Ashkan MonfaredMark J Schnitzer
Sep 21, 2004·Current Opinion in Otolaryngology & Head and Neck Surgery·John S Oghalai
Aug 25, 2001·The Journal of the Acoustical Society of America·W S Rhode, A Recio
Feb 1, 2003·The Journal of the Acoustical Society of America·Anand A ParthasarathiAlfred L Nuttall
Mar 27, 2003·The Journal of the Acoustical Society of America·Andrei N Lukashkin, Ian J Russell
Apr 3, 2004·The Journal of the Acoustical Society of America·Elizabeth S Olson
Nov 4, 2005·The Journal of the Acoustical Society of America·John J GuinanHolden Cheng
Mar 12, 2009·The Journal of the Acoustical Society of America·Douglas H KeefeWalt Jesteadt
Apr 10, 2009·The Journal of the Acoustical Society of America·Skyler G JenningsMichael G Heinz
Nov 10, 2009·The Journal of the Acoustical Society of America·Ryan DeeterSumitrajit Dhar
Sep 8, 2010·The Journal of the Acoustical Society of America·Elin Roverud, Elizabeth A Strickland
Oct 9, 2012·The Journal of the Acoustical Society of America·Skyler G Jennings, Elizabeth A Strickland
Mar 30, 2012·Journal of Neurophysiology·Wei Zhao, Sumitrajit Dhar
Nov 10, 2006·Journal of Neurophysiology·Keith N DarrowM Charles Liberman
Jul 3, 2009·Journal of Neurophysiology·Richard BoyleStephen M Highstein
Jul 25, 2009·PLoS Computational Biology·Richard D RabbittWilliam E Brownell
Apr 23, 2009·PloS One·Kathryn D BrenemanRichard D Rabbitt
May 6, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Guillaume AndéolAnnie Moulin
Jun 24, 1998·The Journal of the Acoustical Society of America·T JanssenW Arnold
Dec 19, 1998·The Journal of the Acoustical Society of America·A J Oxenham, C J Plack
Jan 28, 1999·The Journal of the Acoustical Society of America·M L Hicks, S P Bacon
Jul 31, 2009·The Journal of the Acoustical Society of America·Yi-Wen Liu, Stephen T Neely

❮ Previous
Next ❯

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.