Harmonic subtraction for evaluating right ventricle ejection fraction from planar equilibrium radionuclide angiography

The International Journal of Cardiovascular Imaging
Dacian V BontaNaomi P Alazraki

Abstract

We report an initial investigation of a subtraction-based method to estimate right ventricle ejection fraction (RVEF) from ECG-gated planar equilibrium radionuclide angiography (ERNA) data. Twenty-six consecutive patients referred for scintigraphic evaluation of cardiac function prior to chemotherapy had ECG-gated first-pass (FP) imaging and ERNA imaging performed following the same radiotracer injection. RVEF was computed from FP images (RVEFFP) and separately from ERNA images (RVEFERNA). Standard methods for computing ejection fractions were used to obtain RVEFFP values. RVEFERNA values were obtained using harmonic subtraction of the left ventricular contribution from a biventricular region of interest contoured on the equilibrium images acquired in the shallow right anterior oblique projection. Clinically acquired chest CT data were used to derive information regarding the relative position of the left and right ventricle and about the presence of pulmonary artery enlargement. Computation of RVEFERNA was successful for each of the 26 patients. Computation of RVEFFP failed for four patients. For the 22 patients for which RVEF was computed using both methods, the average RVEFFP was 49% and the average RVEFERNA was 51%, with co...Continue Reading

References

Mar 13, 2002·Academic Radiology·Matthew A KupinskiGeorge A Kastis
Feb 7, 2006·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Roberto M LangUNKNOWN European Association of Echocardiography, European Society of Cardiology
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Dec 3, 2011·Journal of the American College of Cardiology·Mariëlle C van de VeerdonkAnton Vonk-Noordegraaf
Dec 30, 2014·The European Respiratory Journal·Pierre-Yves CourandVincent Cottin

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