Harnessing scorpionate ligand equilibria for modeling reduced nickel superoxide dismutase intermediates

Inorganic Chemistry
Huaibo MaMichael P Jensen

Abstract

Hydrotris(3-phenyl-5-methylpyrazoyl)boratonickel(II) complexes with organoxanthate or dithiocarbamate coligands equilibrate between kappa(2)- and kappa(3)-chelation modes of the scorpionate ligand in solution, connecting N2S2 square-planar and N3S2 pyramidal ligand fields and a spin crossover. The complexes also exhibit quasi-reversible oxidations at low anodic potentials, thus modeling the structure, dynamics, and redox reactivity of the reduced NiSOD active site.

References

Jan 1, 1975·FEBS Letters·J BridgenF Northrop
Nov 23, 2000·Nature·T Finkel, N J Holbrook
Jan 15, 2004·Journal of the American Chemical Society·Peter A BryngelsonMichael J Maroney
Apr 6, 2004·Current Opinion in Chemical Biology·Anne-Frances Miller
Jun 3, 2004·Proceedings of the National Academy of Sciences of the United States of America·Jochen WuergesKristina Djinovic Carugo
Jun 24, 2004·Biochemistry·David P BarondeauElizabeth D Getzoff
Apr 14, 2005·Journal of the American Chemical Society·Adam T FiedlerThomas C Brunold
Apr 26, 2005·Inorganic Chemistry·Vladimir Pelmenschikov, Per E M Siegbahn
Jun 8, 2006·Journal of the American Chemical Society·Vladimir Pelmenschikov, Per E M Siegbahn

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Citations

Nov 21, 2012·Inorganic Chemistry·Shengwen LiangMichael P Jensen
Jul 4, 2009·Inorganic Chemistry·Roxanne M JenkinsMarcetta Y Darensbourg
Dec 17, 2009·Inorganic Chemistry·Mary E KrauseJennifer S Laurence
Dec 22, 2009·Dalton Transactions : an International Journal of Inorganic Chemistry·Matthew B JonesCora E MacBeth
Jan 7, 2011·Dalton Transactions : an International Journal of Inorganic Chemistry·David J HardingHarry Adams
Nov 19, 2020·Dalton Transactions : an International Journal of Inorganic Chemistry·Obaid Ali QamarHuaibo Ma
Mar 26, 2009·Inorganic Chemistry·Patrick J DesrochersTiffany N Linz
Dec 17, 2009·Inorganic Chemistry·Swarup ChattopadhyayMichael P Jensen
Mar 29, 2011·Journal of the American Chemical Society·Huaibo MaMichael P Jensen
Dec 18, 2012·Biochemistry·Ellen P BroeringTodd C Harrop

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