PMID: 3746799Jul 1, 1986Paper

Has the incidence of radiation-induced bowel damage following treatment of uterine carcinoma changed in the last 20 years?

Journal of the Royal Society of Medicine
T G Allen-MershC V Mann

Abstract

Radiation-induced bowel damage occurred in 4.3% of patients treated primarily by irradiation for uterine carcinoma during the period 1962-1982. There has been a progressive rise in the incidence of radiation damage and radiation-induced rectovaginal fistula during this 20-year period. Radiation from intracavitary sources was a contributory factor in 92% of injured cases. The rising incidence of bowel damage in our patients may be due to an increase in the number of patients receiving a high rectal dose from the intracavitary source. There was a significantly (P less than 0.01) higher incidence of radiation injury in cases of cervical carcinoma compared to endometrial carcinoma. This was because cervical carcinoma tended to present at a more advanced stage than endometrial carcinoma and was more frequently treated with combined external and intracavitary irradiation. There was no significant increase in the incidence of complications among patients undergoing hysterectomy.

References

Sep 18, 1965·Lancet·D O'ConnellW E Liversage
Nov 15, 1972·American Journal of Obstetrics and Gynecology·U Villasanta
Feb 1, 1970·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·M F StrockbineG H Fletcher
Jan 1, 1981·Clinical Radiology·H F Hope-StoneS A Scholnick
Apr 1, 1964·American Journal of Obstetrics and Gynecology·H L KOTTMEIER

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Citations

Aug 1, 1987·The British Journal of Surgery·R B Galland, J Spencer
Oct 1, 1993·Diseases of the Colon and Rectum·T NakadaH Kakizaki
Nov 17, 2000·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·N Y HaboubiR J James
May 24, 2017·Technology in Cancer Research & Treatment·Mumtaz AnwarSafrun Mahmood
Aug 1, 1989·Diseases of the Colon and Rectum·H H KimoseP Wara
Jun 2, 2007·Diseases of the Colon and Rectum·Ramaiyer Raghu Raman
May 1, 1992·The British Journal of Surgery·S A HolmesW F Hendry
Apr 1, 1994·International Journal of Colorectal Disease·D M SedgwickA Ferguson
Aug 5, 2021·Journal of Crohn's & Colitis·Roger FeakinsMonika Tripathi

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