PMID: 18183791Jan 11, 2008Paper

Hashimoto's thyroiditis in children and adolescents: a retrospective study on clinical, epidemiological and laboratory properties of the disease

Journal of Pediatric Endocrinology & Metabolism : JPEM
H DemirbilekN Yordam

Abstract

Hashimoto's thyroiditis (HT) is the most common cause of goiter and acquired hypothyroidism in children and adolescents in iodine replete areas. To find out the clinical, epidemiological and laboratory characteristics of the disease in childhood, we reviewed files of 162 children and adolescents with HT followed in the Department of Pediatric Endocrinology, Hacettepe University Faculty of Medicine. Female patients constituted 86.4% (n = 140) of all patients with a female:male ratio of 6.4. Mean age at diagnosis was 11.4 +/- 2.97 years (age range 4.4-16.5 years). At the time of diagnosis 43.2% of the patients (n = 70) were euthyroid, 24.1% (n = 39) had subclinical hypothyroidism, 21% (n = 34) had overt hypothyroidism, and 8.6% (n = 14) had overt and 3.1% (n = 5) subclinical hyperthyroidism. Autoimmune thyroiditis is more frequent in females, and increases in frequency over age during childhood and adolescence. At the time of diagnosis, frequency of overt and subclinical hypothyroidism is similar to that of euthyroid goiter.

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Citations

Feb 22, 2012·The Tohoku Journal of Experimental Medicine·Ayhan KilicMehmet Yokusoglu
Mar 31, 2011·Journal of Clinical Research in Pediatric Endocrinology·Ayça Törel ErgürMerih Berberoğlu
Jan 13, 2009·Clinical and Experimental Immunology·G Guerra-JuniorM Palandi De Mello
May 25, 2012·Diagnostic Cytopathology·Jasleen KaurPranab Dey
Mar 4, 2020·Journal of Pediatric Endocrinology & Metabolism : JPEM·Aysel Burcu Palandokenlier IbiliMehmet Emre Atabek
Apr 24, 2014·Journal of Pediatric Endocrinology & Metabolism : JPEM·Hae Sang Lee, Jin Soon Hwang
Aug 16, 2019·Ocular Immunology and Inflammation·Hasan KiziltoprakZehra Aycan
May 3, 2011·Journal of Pediatric Endocrinology & Metabolism : JPEM·Murat DoğanMehmet Selcuk Bektas
Feb 11, 2021·Diagnostics·Cristina Mihaela CepehaDana Stoian
Jun 15, 2021·Journal of Pediatric Endocrinology & Metabolism : JPEM·İrem Ceren ErbaşOlcay Evliyaoğlu

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