Hass Avocado Inclusion in a Weight-Loss Diet Supported Weight Loss and Altered Gut Microbiota: A 12-Week Randomized, Parallel-Controlled Trial

Current Developments in Nutrition
Susanne M HenningZhaoping Li

Abstract

Avocados contain fiber, lutein, and vitamin E, and they are a rich source of MUFAs. The effect of including an avocado daily as part of a hypocaloric weight-loss diet on weight loss is not known. The aim of this study was to determine the effect of daily avocado consumption as part of a hypocaloric diet on weight loss, body composition, satiety, biomarkers of inflammation, and intestinal microbiota composition. In this randomized, parallel-controlled, open-label, 2-arm intervention study, 51 healthy overweight/obese women and men were assigned to a hypocaloric diet with 1 Hass avocado daily (AVO; n = 24) or a hypocaloric diet (CTRL; n = 27) without daily avocado for 12 wk. Serum markers and intestinal microbiota were analyzed at baseline and week 12. Both groups experienced significant weight loss, decrease in BMI (in kg/m2), total body fat, and visceral adipose tissue, respectively (AVO: -2.3 ± 2 kg, -0.8 ± 0.8, -1.1% ± 2%, and -81.2 ± 118 g; CTRL: -2.6 ± 3.6 kg, -0.9 ± 1, -1.5% ± 2%, and -87.4 ± 216 g). We observed a significant decrease in serum glucose over time in the control group compared with the AVO group. There was no change between the groups in serum triglyceride, but a significant decrease from baseline to 12 wk wa...Continue Reading

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Citations

Jan 18, 2020·Annual Review of Food Science and Technology·Yanhui Han, Hang Xiao
Jun 18, 2020·Frontiers in Nutrition·Nikki A Ford, Ann G Liu
Nov 5, 2019·Frontiers in Nutrition·Jananee MuralidharanJordi Salas-Salvadó

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Methods Mentioned

BETA
pregnancy test
X-Ray

Clinical Trials Mentioned

NCT02953158

Software Mentioned

enCORE CoreScan
BLASTn
SAS
EMPeror
QIIME

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