PMID: 3754244Jan 1, 1986Paper

Hb Himeji or beta 140 (H18) Ala----Asp. A slightly unstable hemoglobin with increased beta N-terminal glycation

Hemoglobin
Y OhbaK Hitaka

Abstract

A fast-moving abnormal hemoglobin found in a diabetic patient was identified as beta 140 (H18) Ala----Asp. It comprised about 40% of the total hemoglobin. The beta N-terminal glycation in the abnormal hemoglobin was estimated to be 3 times as much as that in Hb A in the same blood sample. The abnormal hemoglobin was slightly unstable. Oxygen affinity of the stripped hemoglobin was decreased, but that of red cells from the carrier was slightly higher than normal because of the reduced effect of 2,3-diphosphoglycerate.

References

Dec 1, 1976·FEBS Letters·R Flückiger, K H Winterhalter
Jul 6, 1968·Nature·J B CleggD J Weatherall
Jan 1, 1983·Hemoglobin·K IshiguroK Nakaizumi
Mar 12, 1982·Clinica Chimica Acta; International Journal of Clinical Chemistry·Y OhbaM Hirano

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Citations

Apr 18, 2001·Diabetes/metabolism Research and Reviews·W J SchnedlG J Krejs
Sep 30, 1987·Clinica Chimica Acta; International Journal of Clinical Chemistry·F VandeneschJ Delaunay
Jul 24, 2002·Clinica Chimica Acta; International Journal of Clinical Chemistry·Toyofumi NakanishiSatoshi Nishimura
Oct 10, 2014·Indian Journal of Clinical Biochemistry : IJCB·Bratati SinghSeema Das
Feb 17, 2015·Clinica Chimica Acta; International Journal of Clinical Chemistry·Xinqi ChengWei Su
Sep 16, 2015·Internal Medicine·Shinobu TamuraCeleste Bento
Jun 7, 2011·Clinica Chimica Acta; International Journal of Clinical Chemistry·Eijun NishiharaAkira Miyauchi
Feb 1, 2011·Clinical Chemistry·Alina-Gabriela SofronescuYusheng Zhu
Jan 1, 1989·Hemoglobin·M C MartinsT H Huisman
Jul 27, 2017·Journal of Medical Case Reports·Vânia GuedesDavide Carvalho
Jan 23, 2020·AACE Clinical Case Reports·Maali MilhemNesreen BenHamed
Jul 14, 2020·Journal of Clinical Laboratory Analysis·Rui LiXiuming Zhang
Dec 19, 2020·Endocrinología, Diabetes Y Nutrición·Fernando García UrruzolaEdelmiro Menéndez Torre

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