HbA1c and retinal sensitivity in diabetics using microperimetry

Journal of Optometry
Sharanjeet-KaurNor Fariza Ngah

Abstract

The purpose of this study was to determine the relationship between HbA1c values and retinal sensitivity at central 10° using the MP-1 microperimeter. A prospective study was carried out on 32 healthy subjects (control group) and 60 diabetic patients. The diabetic patients were divided into 2 groups. Group 1 comprised of 30 patients without diabetic retinopathy (DR) and group 2 had 30 patients with mild non-proliferative DR. A full-threshold microperimetry of the central 10° of retina (the macula) was performed on all subjects, utilizing 32 points with the MP-1. The relationship between light sensitivity and HbA1c value was calculated using linear regression analysis. Total mean sensitivity at 10° for group 1 without DR, group 2 with mild NPDR and control group were 18.67±0.83, 17.98±1.42 and 19.45±0.34 (dB), respectively. There was a significant difference in total mean retinal sensitivity at 10° between the 3 groups (F(2,89)=18.14, p=0.001). A simple linear regression was calculated to predict HbA1c based on retinal sensitivity. A significant regression equation was found (F(1,90)=107.61, p=0.0001, with an R2 of 0.545). The linear regression analysis revealed that there was a 0.64dB decline in mean retinal sensitivity within ...Continue Reading

Citations

Oct 31, 2018·Journal of Telemedicine and Telecare·Prima MoinulVarun Chaudhary
Oct 12, 2019·Translational Vision Science & Technology·Husam AlghanemNaheed W Khan
Mar 7, 2021·Diagnostics·Rodolfo MastropasquaLisa Toto
Mar 25, 2021·Investigative Ophthalmology & Visual Science·Giovanni MontesanoRuth E Hogg

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