PMID: 229879Dec 1, 1979

HDL lipids in close relatives of coronary heart disease patients. Environmental and genetic influences

Atherosclerosis
D PomettaC Jornot

Abstract

Female first-degree relatives of CHD patients differed, after the age of forty, from the normal control population by their low HDL cholesterol. Between the ages of 20 and 40 years a slight but significant increase in HDL triglycerides was observed. Except for hormonal contraception which induces significant lowering of HDL cholesterol in the first degree relatives, the observed differences in HDL lipids did not seem related to environmental factors but rather to be genetically determined. In contrast, the low HDL cholesterol observed in the wives of the CHD patients appeared to be related to differences in alcohol intake.

References

Apr 1, 1978·Metabolism: Clinical and Experimental·J J AlbersW R Hazzard
Jul 6, 1978·The New England Journal of Medicine·D D BradleyS Ramcharan
Feb 23, 1976·JAMA : the Journal of the American Medical Association·M P SternP D Wood

Citations

Oct 1, 1988·The American Journal of Cardiology·L B Jorde, R R Williams
Jul 1, 1984·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·E J Schaefer
Oct 24, 2000·International Journal of Dermatology·A M Klioze, F A Ramos-Caro
Jul 1, 1995·Scandinavian Journal of Clinical and Laboratory Investigation·J EritslandM Abdelnoor
Jan 1, 1980·Acta geneticae medicae et gemellologiae·H Boman

Related Concepts

Epicholesterol
Coronary Heart Disease
Alpha-1 Lipoprotein
LDL-1
Lipoproteins, VLDL1
Triglycerides

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