Head-to-head comparison of a CZT-based all-purpose SPECT camera and a dedicated CZT cardiac device for myocardial perfusion and functional analysis.

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
Alessia GimelliPaolo Marzullo

Abstract

To compare the outputs of a novel all-purpose SPECT camera equipped with CZT detectors (Discovery NM/CT 670) with the state-of-the-art represented by a dedicated CZT (Alcyone, Discovery 530c) cardiac camera in patients submitted to myocardial perfusion imaging (MPI). We included 19 patients that underwent sequential low-dose 99mTc-tetrofosmin (148-185 MBq during stress and 296-370 MBq at rest) MPI with Alcyone and Discovery 670 cameras. Quantitative (% tracer's uptake) and semi-quantitative analyses of perfusion data were performed for each scan. Moreover, major left ventricular (LV) functional and structural parameters were derived from each camera and compared. The two cameras showed excellent correlation for segmental myocardial % uptake at stress (R = 0.90; P < 0.001) and at rest (R = 0.88; P < 0.001) with narrow Bland-Altman limits of agreement. The level of diagnostic agreement of Discovery 670 and Alcyone cameras regarding perfusion analysis was excellent (Cohen's κ 0.85). Similarly, the two cameras showed excellent correlation in the evaluation of LV ejection fraction (R = 0.95), peak filling rate (R = 0.97), and mass (R = 0.98). Our preliminary results suggest that MPI with an all-purpose Discovery 670 CZT-SPECT camera...Continue Reading

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Feb 6, 2016·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Alessia GimelliPaolo Marzullo
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Apr 10, 2019·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Maxime MorelleAlban Bailliez

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Citations

Oct 28, 2019·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Piotr Slomka
May 16, 2020·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Marek SalaTomáš Holeček
Aug 11, 2020·Current Cardiology Reports·Riccardo Liga, Danilo Neglia
Apr 24, 2021·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·P B BonnefoyR Ahond-Vionnet

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