Headache and temporal arteritis: when to suspect and how to manage.

Current Pain and Headache Reports
Stephanie J Nahas

Abstract

Temporal arteritis, also termed giant cell arteritis, is one of the vasculitides affecting large and medium sized cranial arteries, particularly of the carotid tree. Clinical manifestations may vary from the classic constellation of temporal headache in the elderly accompanied by constitutional signs, jaw claudication, and visual symptoms; therefore, a high index of clinical suspicion may be necessary to identify the disorder. Once suspected, immediate treatment is crucial while exploring any number of diagnostic tools to confirm or refute the diagnosis, since morbidity from untreated temporal arteritis can be devastating. At the same time, achieving a definitive diagnosis is paramount, as treatment can be toxic with significant morbidity of its own. Temporal artery biopsy remains the gold standard, but noninvasive diagnostic approaches are being refined. Corticosteroids remain the cornerstone of treatment, but are ineffective for, not tolerated by, or contraindicated in some individuals, necessitating the exploration of alternatives.

References

Jan 1, 1976·Survey of Ophthalmology·J F Cullen, J A Coleiro
Nov 14, 1997·The New England Journal of Medicine·W A SchmidtE J Gromnica-Ihle
Feb 20, 1999·Arthritis and Rheumatism·A BrackC M Weyand
Apr 12, 2000·Seminars in Ophthalmology·A G Neff, E M Greifenstein
Jan 12, 2002·JAMA : the Journal of the American Medical Association·Gerald W Smetana, Robert H Shmerling
Feb 13, 2002·Arthritis and Rheumatism·Cornelia M WeyandJörg J Goronzy
Apr 26, 2002·The British Journal of Ophthalmology·N Ray-ChaudhuriM R Dayan
Jul 13, 2002·Arthritis and Rheumatism·Gary S HoffmanUNKNOWN International Network for the Study of Systemic Vasculitides
Mar 8, 2003·Ophthalmology·Rod ForoozanPeter J Savino
Jan 21, 2004·Current Pain and Headache Reports·Morris Levin
Feb 26, 2004·Cephalalgia : an International Journal of Headache·UNKNOWN Headache Classification Subcommittee of the International Headache Society
Apr 13, 2004·Arthritis and Rheumatism·Gideon NesherMoshe Sonnenblick
Mar 2, 2005·Annals of Internal Medicine·Fotini B KarassaJohn P A Ioannidis
Jun 1, 2005·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·T N Ward, M Levin
Sep 30, 2006·Arthritis and Rheumatism·Michael S LeeGary S Hoffman
Jan 26, 2007·Investigative Ophthalmology & Visual Science·Ryan D Niederkohr, Leonard A Levin
May 2, 2007·Annals of Internal Medicine·Gary S HoffmanUNKNOWN Infliximab-GCA Study Group
Sep 22, 2007·AJNR. American Journal of Neuroradiology·T A BleyO Wieben
Jan 29, 2008·Seminars in Arthritis and Rheumatism·Maria J Lopez-DiazMiguel A Gonzalez-Gay
Apr 2, 2008·Joint, Bone, Spine : Revue Du Rhumatisme·Valérie Devauchelle-PensecAlain Saraux
Apr 17, 2008·Annals of the Rheumatic Diseases·C MukhtyarUNKNOWN European Vasculitis Study Group
Jul 3, 2008·Vascular Medicine·Federico Tatò, Ulrich Hoffmann
Feb 21, 2009·The Journal of Rheumatology·Gabriel S BreuerRonit Nesher
Jul 10, 2009·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·S S L ChewH V Danesh-Meyer
Aug 29, 2009·European Journal of Internal Medicine·B MaríJ Oristrell
Oct 1, 2009·Arthritis and Rheumatism·Miguel A Gonzalez-GayJavier Llorca
Oct 27, 2009·Annals of the Rheumatic Diseases·Tanaz A KermaniKenneth J Warrington
Jan 26, 2010·Journal of Magnetic Resonance Imaging : JMRI·Julia GeigerMichael Markl

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Citations

Apr 16, 2013·Current Pain and Headache Reports·Siddharth Kapoor
Oct 29, 2013·Current Pain and Headache Reports·Noa SchwartzJohannes Nowatzky
Sep 21, 2013·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Bharat KumarKristine M Lohr
Mar 5, 2016·Internal Medicine·Shin-Ichi TokushigeYasushi Shiio
Oct 30, 2013·The Neurohospitalist·Christian M Cabrera KangBeau B Bruce
Mar 24, 2016·Neurocritical Care·Laxmi P DhakalWilliam D Freeman

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