Health and economic implications of HPV vaccination in the United States.

The New England Journal of Medicine
Jane J Kim, Sue J Goldie

Abstract

The cost-effectiveness of prophylactic vaccination against human papillomavirus types 16 (HPV-16) and 18 (HPV-18) is an important consideration for guidelines for immunization in the United States. We synthesized epidemiologic and demographic data using models of HPV-16 and HPV-18 transmission and cervical carcinogenesis to compare the health and economic outcomes of vaccinating preadolescent girls (at 12 years of age) and vaccinating older girls and women in catch-up programs (to 18, 21, or 26 years of age). We examined the health benefits of averting other HPV-16-related and HPV-18-related cancers, the prevention of HPV-6-related and HPV-11-related genital warts and juvenile-onset recurrent respiratory papillomatosis by means of the quadrivalent vaccine, the duration of immunity, and future screening practices. On the assumption that the vaccine provided lifelong immunity, the cost-effectiveness ratio of vaccination of 12-year-old girls was $43,600 per quality-adjusted life-year (QALY) gained, as compared with the current screening practice. Under baseline assumptions, the cost-effectiveness ratio for extending a temporary catch-up program for girls to 18 years of age was $97,300 per QALY; the cost of extending vaccination of...Continue Reading

References

Dec 1, 1995·Archives of Otolaryngology--head & Neck Surgery·C S Derkay
Apr 1, 1993·Medical Decision Making : an International Journal of the Society for Medical Decision Making·D G FrybackP A Martin
Aug 2, 2000·Archives of Otolaryngology--head & Neck Surgery·D BishaiK Shah
Mar 5, 2002·British Journal of Cancer·S FranceschiN Muñoz
Apr 23, 2002·JAMA : the Journal of the American Medical Association·Thomas C WrightUNKNOWN ASCCP-Sponsored Consensus Conference
Dec 10, 2002·CA: a Cancer Journal for Clinicians·Debbie SaslowUNKNOWN American Cancer Society
Jan 21, 2003·Emerging Infectious Diseases·Gillian D Sanders, Al V Taira
Jan 25, 2003·American Journal of Epidemiology·Rachel L WinerLaura A Koutsky
Jan 31, 2003·British Journal of Cancer·G M CliffordS Franceschi
May 27, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ralph P InsingaEvan R Myers
Aug 14, 2003·JAMA : the Journal of the American Medical Association·Shalini L Kulasingam, Evan R Myers
Nov 25, 2003·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·UNKNOWN American College of Obstetricians and Gynecologists
Apr 22, 2004·Journal of the National Cancer Institute·Sue J GoldieEduardo Franco
Sep 16, 2004·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Hans-Georg EichlerBengt Jönsson
Nov 20, 2004·Emerging Infectious Diseases·Al V TairaGillian D Sanders
Sep 5, 2006·Vaccine·Margaret StanleyIan Frazer
Sep 5, 2006·Vaccine·D Maxwell Parkin, Freddie Bray
Mar 1, 2007·JAMA : the Journal of the American Medical Association·Eileen F DunneLauri E Markowitz
Mar 21, 2007·Emerging Infectious Diseases·Elamin H ElbashaRalph P Insinga
Mar 23, 2007·The Lancet Infectious Diseases·Anthony T NewallC Raina MacIntyre
May 15, 2007·The New England Journal of Medicine·UNKNOWN FUTURE II Study Group
May 15, 2007·The New England Journal of Medicine·Suzanne M GarlandUNKNOWN Females United to Unilaterally Reduce Endo/Ectocervical Disease (FUTURE) I Investigators
May 29, 2007·American Journal of Epidemiology·Jane J KimSue J Goldie
Jul 4, 2007·Vaccine·Sue J GoldieEduardo L Franco
Aug 31, 2007·American Journal of Epidemiology·Sanjay Basu, Alison P Galvani
Oct 2, 2007·American Journal of Obstetrics and Gynecology·Thomas C WrightUNKNOWN 2006 American Society for Colposcopy and Cervical Pathology-sponsored Consensus Conference
Mar 4, 2008·Journal of the National Cancer Institute·Jeremy D Goldhaber-FiebertSue J Goldie

❮ Previous
Next ❯

Citations

Apr 24, 2009·Current Treatment Options in Oncology·Amy A Hakim, Tri A Dinh
Dec 11, 2008·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Ana Oaknin, Ma Pilar Barretina
Aug 28, 2012·The Lancet Infectious Diseases·Talía MalagónMarc Brisson
Aug 28, 2010·The British Journal of Nutrition·I Lenoir-WijnkoopM J C Nuijten
Nov 11, 2008·Nature Biotechnology·Saurabh Aggarwal
Aug 22, 2008·The New England Journal of Medicine·Charlotte J Haug
Aug 20, 2010·Sexual Health·Philippe Beutels, Mark Jit
Nov 7, 2009·Journal of American College Health : J of ACH·Jessica R Sandfort, Andrew Pleasant
Jul 12, 2011·The Journal of Infectious Diseases·Tjalke A WestraJan C Wilschut
Jul 3, 2009·Journal of the National Cancer Institute·Inge M C M de KokJ Dik F Habbema
Sep 9, 2011·Journal of the National Cancer Institute·Sue J Goldie, Norman Daniels
Oct 30, 2012·Journal of the National Cancer Institute·Nicolas Van de VeldeMarc Brisson
Jun 19, 2012·Diseases of the Colon and Rectum·Scott R SteeleUNKNOWN Standards Practice Task Force of the American Society of Colon and Rectal Surgeons
Nov 20, 2009·Current Opinion in Obstetrics & Gynecology·Diane M Harper
Jan 15, 2013·Clinical Obstetrics and Gynecology·Christopher J Darus, Jennifer J Mueller
Jan 16, 2013·Clinical Obstetrics and Gynecology·Katharine M Esselen, Sarah Feldman
Feb 27, 2009·Current Opinion in Pediatrics·Hal B Jenson
Apr 24, 2010·Sexually Transmitted Diseases·Paul L ReiterNoel T Brewer
Sep 25, 2012·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Jennifer L MossNoel T Brewer
Apr 2, 2011·BMC Public Health·Vernon J LeeMei Yin Tok
Jul 13, 2013·BMC Public Health·Piergiorgio CrosignaniGian Vincenzo Zuccotti
Feb 27, 2009·BMC Public Health·Paolo Giorgi RossiAntonio Federici
Jan 13, 2010·BMC Health Services Research·Pang-Hsiang LiuJung-Der Wang
Oct 5, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Anil K ChaturvediMaura L Gillison
Mar 4, 2009·PharmacoEconomics·Maurizio Bonati, Silvio Garattini
Dec 29, 2011·PharmacoEconomics·Adam J N RaymakersCarlo A Marra
Jan 21, 2014·Infectious Agents and Cancer·Iacopo BaussanoSilvia Franceschi
Nov 24, 2011·ISRN Obstetrics and Gynecology·Diane M Harper, Stephen L Vierthaler
Aug 2, 2014·American Journal of Epidemiology·Nicole G CamposJane J Kim

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Emerging Infectious Diseases
Al V TairaGillian D Sanders
Emerging Infectious Diseases
Elamin H ElbashaRalph P Insinga
© 2022 Meta ULC. All rights reserved