Health and Neurodevelopment of Children Born to Opioid-Dependent Mothers at School Entry.

Journal of Developmental and Behavioral Pediatrics : JDBP
Samantha J LeeLianne J Woodward

Abstract

To examine the school readiness of a regional cohort of prenatally methadone-exposed children across 5 domains and to examine factors contributing to impairment risk. Data were drawn from a single-center, prospective longitudinal study. One hundred children born to women in methadone maintenance treatment and 110 randomly identified non-methadone-exposed children were studied from birth (2003-2008) to age 4.5 years. At 4.5 years, children underwent comprehensive assessment of their physical/motor development, social-emotional skills, approaches to learning, language development, and cognitive functioning. Predictors of children's overall school readiness were examined, including the extent of prenatal substance exposure (number and quantity of different substances), social risk, maternal mental health, infant clinical factors, and the quality of the home environment at age 18 months Home Observation for Measurement of the Environment (HOME) score. Methadone-exposed children had higher rates of delay/impairment across all outcome domains (odds ratios 4.0-5.3), with 72% impaired in at least 1 domain. Multiple problems were also common, affecting 48% of methadone-exposed children compared with 15% of control children. The mean num...Continue Reading

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Citations

Aug 2, 2020·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Hamed FanaeiMorad Bornavard
Jan 13, 2021·Research on Child and Adolescent Psychopathology·Julia JaekelLianne J Woodward
Feb 17, 2021·European Child & Adolescent Psychiatry·Monica SarfiStine Lehmann
Feb 19, 2021·Archives of Disease in Childhood. Fetal and Neonatal Edition·James P BoardmanLori A Devlin
Jan 20, 2021·Developmental Medicine and Child Neurology·Terri A LevineLianne J Woodward

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