Health benefit of vegetable/fruit juice-based diet: Role of microbiome

Scientific Reports
Susanne M HenningZhaoping Li

Abstract

The gut microbiota is an important contributor to human health. Vegetable/fruit juices provide polyphenols, oligosaccharides, fiber and nitrate (beet juice), which may induce a prebiotic-like effect. Juice-based diets are becoming popular. However, there is a lack of scientific evidence of their health benefits. It was our hypothesis that changes in the intestinal microbiota induced by a juice-based diet play an important role in their health benefits. Twenty healthy adults consumed only vegetable/fruit juices for 3 days followed by 14 days of customary diet. On day 4 we observed a significant decrease in weight and body mass index (p = 2.0E-05), which was maintained until day 17 (p = 3.0E-04). On day 4 the proportion of the phylum Firmicutes and Proteobacteria in stool was significantly decreased and Bacteroidetes and Cyanobacteria was increased compared to baseline and was partially reversed on day 17. On day 4 plasma and urine nitric oxide was increased by 244 ± 89% and 450 ± 360%, respectively, and urinary lipid peroxidation marker malondialdehyde was decreased by 32 ± 21% compared to baseline. General well-being score was increased at the end of the study. In summary a 3-day juice-based diet altered the intestinal microbio...Continue Reading

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Citations

Apr 26, 2018·Acta Physiologica·M CarlströmE Weitzberg
Apr 21, 2018·Molecular Nutrition & Food Research·Jieping YangZhaoping Li
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Methods Mentioned

BETA
MDA
PCR

Clinical Trials Mentioned

NCT02377063

Software Mentioned

BLASTn
GraphPad Prism
Quantitative Insights Into Microbial Ecology ( QIIME )
PERMDISP
SPSS Statistics
QIIME
EMPeror
PICRUST

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