Health Care Utilization and Burden of Diabetic Ketoacidosis in the U.S. Over the Past Decade: A Nationwide Analysis.

Diabetes Care
Dimpi DesaiUlrich K Schubart

Abstract

Diabetes is one of the most common chronic diseases and a leading cause of morbidity and mortality in the U.S. Although our ability to treat diabetes and its associated complications has significantly improved, presentation with uncontrolled diabetes leading to ketoacidosis remains a significant problem. We aimed to determine the incidence and costs of hospital admissions associated with diabetic ketoacidosis (DKA). We reviewed the National Inpatient Sample database for all hospitalizations in which DKA (ICD-9 codes 250.10, 250.11, 250.12, and 250.13) was the principal discharge diagnosis during 2003-2014 and calculated the population incidence by using U.S. census data. Patients with ICD-9 codes for diabetic coma were excluded because the codes do not distinguish between hypoglycemic and DKA-related coma. We then analyzed changes in temporal trends of incidence, length of stay, costs, and in-hospital mortality by using the Cochrane-Armitage test. There were 1,760,101 primary admissions for DKA during the study period. In-hospital mortality for the cohort was 0.4% (n = 7,031). The total number of hospital discharges with the principal diagnosis of DKA increased from 118,808 in 2003 to 188,965 in 2014 (P < 0.0001). The length of...Continue Reading

References

Jul 1, 1991·Diabetes Care·R M AndersonH W Neighbors
Aug 1, 1986·Medical Care·H Temkin-Greener
Oct 1, 1994·Diabetes Care·W H PolonskyC F Cole
Apr 1, 1997·Diabetes Care·O Pinhas-HamielP S Zeitler
Feb 24, 2001·Diabetes Care·A E KitabchiB M Wall
Jan 15, 2003·The Journal of School Health·UNKNOWN Office on Smoking and Health, Division of Adolescent and School Health National Center for Chronic Disease Prevention and He
Sep 24, 2004·Diabetic Medicine : a Journal of the British Diabetic Association·V ZdravkovicJ Hamilton
Mar 24, 2005·Postgraduate Medicine·Fadi NabhanNicholas Emanuele
Mar 8, 2006·Annals of Internal Medicine·Guillermo E UmpierrezAbbas E Kitabchi
Nov 28, 2006·Endocrinology and Metabolism Clinics of North America·Abbas E Kitabchi, Ebenezer A Nyenwe
Mar 3, 2009·Diabetes Care·Lenna L LiuUNKNOWN SEARCH for Diabetes in Youth Study Group
Jul 1, 2009·Diabetes Care·Abbas E KitabchiJoseph N Fisher
Dec 8, 2010·Acta Diabetologica·María L Isidro, Segundo Jorge
Mar 17, 2011·American Journal of Preventive Medicine·Lawrence E BarkerTheodore J Thompson
May 23, 2012·Diabetes Management·Dawn SmileyGuillermo E Umpierrez
Oct 16, 2012·Journal of Diabetes Science and Technology·Baraka FloydGuillermo E Umpierrez
Apr 4, 2015·Case Reports in Medicine·Omar NadhemRoger D Smalligan
May 9, 2015·Pediatric Diabetes·Georgeanna J KlingensmithUNKNOWN Pediatric Diabetes Consortium
May 23, 2015·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Susan S GarfieldMary McBride
Mar 16, 2016·Metabolism: Clinical and Experimental·Ebenezer A Nyenwe, Abbas E Kitabchi
Jun 4, 2016·BMJ : British Medical Journal·Nigel Hawkes
Jul 22, 2016·Diabetes Care·Eberhard Standl, David R Owen
Sep 9, 2017·Diabetes Technology & Therapeutics·Lutz Heinemann, Alan W Carter
Jul 25, 2018·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Alicia ShugartAlexander J Kallen

❮ Previous
Next ❯

Citations

Jan 11, 2019·Journal of Diabetes Science and Technology·Melissa H LeeDavid N O'Neal
Jan 8, 2019·Diabetic Medicine : a Journal of the British Diabetic Association·K K DhatariyaR Fordham
Mar 27, 2019·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Carolina R HurtadoRodolfo J Galindo
Apr 12, 2019·Psychology, Health & Medicine·Brenton LaBarberaJoni Beck
Dec 31, 2019·Diabetes Technology & Therapeutics·Matthew SussmanRobert Griffiths
Sep 19, 2019·The Journal of Clinical Endocrinology and Metabolism·Merlin ThomasPer-Henrik Groop
Oct 28, 2019·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Allen C XuM Cecilia Lansang
Oct 11, 2019·Archives of Disease in Childhood·Ivana RabboneUNKNOWN Diabetes Study Group of the Italian Society for Pediatric Endocrinology and Diabetology (ISPED)
Aug 3, 2019·Pediatrics in Review·Katherine Cashen, Tara Petersen
Feb 12, 2020·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Alon Yehuda MazoriVafa Tabatabaie
May 16, 2020·Nature Reviews. Disease Primers·Ketan K DhatariyaGuillermo E Umpierrez
Aug 10, 2020·Nature Medicine·Lauric A FerratUNKNOWN Committees
Apr 2, 2020·The Journal of International Medical Research·Huifang DaiLielie Zhu
Nov 10, 2020·Current Diabetes Reports·Preethika S EkanayakeKristen Kulasa
Nov 11, 2020·Pediatric Diabetes·Susan KlostermannJennifer Shroff Pendley
Sep 6, 2020·The Journal of Pediatrics·Michelle M PerezBradley C Clark
Dec 15, 2020·Diabetes Research and Clinical Practice·Yukihito SatoHideo Yasunaga
Feb 2, 2021·Pediatric Pulmonology·Keyur DondaFredrick Dapaah-Siakwan
Feb 6, 2021·Curēus·Balraj SinghFayez Shamoon
Feb 3, 2021·Journal of Clinical and Translational Endocrinology Case Reports·William P ZellerWilliam Zeller
Jan 26, 2021·The Journal of Clinical Endocrinology and Metabolism·Akira OkadaTakashi Kadowaki
Oct 15, 2020·Diabetes Care·Kamleshun Ramphul, Jyotsnav Joynauth
May 5, 2021·The Journal of Clinical Endocrinology and Metabolism·Estelle M EverettLauren E Wisk
Jun 21, 2021·Pediatric Research·Keren Smuel-ZilberbergRevital Nimri
Jun 23, 2021·Journal of Medical Economics·Timothy KwaSarnath Chattaraj
Jul 12, 2021·BMC Health Services Research·Steven JamesSean Clark
Oct 5, 2021·Journal of Diabetes Science and Technology·Kevin T NguyenDavid C Klonoff
Jan 7, 2022·The Annals of Pharmacotherapy·Adriana R CarrilloPreeyaporn Sarangarm

❮ Previous
Next ❯

Related Concepts

Related Feeds

American Diabetes Association Journals

Discover the latest diabetes research published by the journals from the American Diabetes Association.