Health care workers and the initiation of treatment for latent tuberculosis infection

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Andrea S GershonJae Yang

Abstract

Despite strong evidence and recommendations supporting the treatment of latent tuberculosis infection, many affected health care workers at risk of acquiring tuberculosis from and potentially transmitting tuberculosis to their patients do not receive treatment. The objective of this study was to determine whether health care workers were less likely than non-health care workers to initiate treatment for latent tuberculosis infection. In this retrospective cohort study that used the disease management database from a specialized downtown Toronto tuberculosis clinic, patients with latent tuberculosis infection were included if they had risk factors for progression of disease and were excluded if they had contraindications to treatment. Our final cohort consisted of 308 patients with latent tuberculosis infection. The overall treatment initiation rate was 58%. We found that, when a number of confounding variables, including age, foreign birth, contact with persons with active tuberculosis, tuberculosis skin test conversion, bacille Calmette-Guérin vaccination, abnormal chest radiograph findings, comorbidities, and income, were considered and/or controlled for, the odds of a health care worker initiating treatment were approximatel...Continue Reading

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Citations

Jan 6, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Elizabeth L CorbettStan Houston
Apr 12, 2008·The Journal of Hospital Infection·V BarsegianM Lindemann
May 18, 2016·BMC Infectious Diseases·Andreas SandgrenMarieke J van der Werf
Jun 9, 2016·BMC Infectious Diseases·Anke L StuurmanMarieke J van der Werf
Mar 12, 2016·PeerJ·Vidya PathakClaudia C Dobler
Apr 7, 2009·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Ekachai SinghatirajMatthew Robinson
Aug 1, 2019·Open Forum Infectious Diseases·Jonathan W UzorkaSandra M Arend
Oct 12, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Esther Arguello PerezArthur E Brown
Sep 26, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Melanie D SwiftM Hassan Murad
Apr 15, 2017·Microbiology Spectrum·Connie A Haley

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